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Tetrahydrothiophene

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Tetrahydrothiophene Basic information

Product Name:
Tetrahydrothiophene
Synonyms:
  • tetrahydro-thiophen
  • Tetramethylene sulphide
  • Tetramethylensulfid
  • Thilane
  • Thiofan
  • THIOPHANE
  • TETRAHYDROTHIOPHENE, 1000MG, NEAT
  • THT
CAS:
110-01-0
MF:
C4H8S
MW:
88.17
EINECS:
203-728-9
Product Categories:
  • Building Blocks
  • C4 to C6
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Thiophenes
Mol File:
110-01-0.mol
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Tetrahydrothiophene Chemical Properties

Melting point:
-96 °C
Boiling point:
119 °C(lit.)
Density 
1 g/mL at 25 °C(lit.)
vapor pressure 
18 mm Hg ( 25 °C)
refractive index 
n20/D 1.504(lit.)
Flash point:
55 °F
storage temp. 
Flammables area
solubility 
immiscible
form 
liquid
Specific Gravity
1.002 (20/4℃)
PH
7 (H2O, 20℃)
explosive limit
1.1-12.1%(V)
Water Solubility 
immiscible
Merck 
14,9218
BRN 
102392
Stability:
Stability Highly flammable. Vapour-air mixtures explosive in some proportions; note low flash point and fairly wide explosion limit range. Heavier than air, so potentially explosive mixtures may travel considerable distances to source of ignition.
CAS DataBase Reference
110-01-0(CAS DataBase Reference)
NIST Chemistry Reference
Thiophene, tetrahydro-(110-01-0)
EPA Substance Registry System
Thiophene, tetrahydro-(110-01-0)
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Safety Information

Hazard Codes 
F,Xn
Risk Statements 
11-20/21/22-36/38-52/53
Safety Statements 
16-23-36/37-61
RIDADR 
UN 2412 3/PG 2
WGK Germany 
2
RTECS 
XN0370000
Autoignition Temperature
202 °C
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29349990
Hazardous Substances Data
110-01-0(Hazardous Substances Data)
Toxicity
LD50 by inhalation in mice: 26.7 mg/l (Carlucci)

MSDS

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Tetrahydrothiophene Usage And Synthesis

Chemical Properties

colourless liquid

Uses

Natural gas odorant.

General Description

A water-white liquid. About the same density as water and insoluble in water. Flash point near 20°F. Vapors heavier than air. Used as a solvent and to make other chemicals.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Organosulfides, such as Tetrahydrothiophene, are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Slow addition of hydrogen peroxide to the thiophene resulted in explosions on three occasions, Chem. Eng. News, 1974, 52(39), 3.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Mildly toxic by inhalation. Flammable liquid. Potentially explosive reaction with hydrogen peroxide. When heated to decomposition it emits toxic fumes of SOx.

Purification Methods

The crude material is purified by crystallisation of the mercuric chloride complex to a constant melting point. It is then regenerated, washed, dried, and fractionally distilled. [Whitehead et al. J Am Chem Soc 73 3632 1951.] It has been dried over Na2SO4 and distilled in a vacuum [Roberts & Friend J Am Chem Soc 108 7204 1986]. [Beilstein 17 I 5, 17 II 15, 17 III/IV 34, 17/1 V 36.]

Tetrahydrothiophene Preparation Products And Raw materials

Raw materials

TetrahydrothiopheneSupplier

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