1-Bromo-4-chloro-2-fluorobenzene Chemical Properties

Boiling point:

91-92 °C/20 mmHg (lit.)

Density 

1.678 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.556(lit.)

Flash point:

198 °F

storage temp. 

Sealed in dry,Room Temperature

form 

Liquid

Specific Gravity

1.678

color 

Clear colorless to pale yellow

Water Solubility 

INSOLUBLE

BRN 

2081083

InChIKey

FPNVMCMDWZNTEU-UHFFFAOYSA-N

CAS DataBase Reference

1996-29-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26-24/25

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29039990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1-Bromo-4-chloro-2-fluorobenzene Usage And Synthesis

Chemical Properties

CLEAR COLORLESS TO PALE YELLOW LIQUID

Uses

1-Bromo-4-chloro-2-fluorobenzene may be used in the preparation of benzonorbornadiene derivative. It may also be used as a starting material in the multi-step synthesis of AZD3264, an IKK2 (inhibitor of nuclear factor κ-B kinase-2) inhibitor.

Uses

A 2,4-dihalofluorobenzene derivative with antibacterial and antifungal activities.

General Description

1-Bromo-4-chloro-2-fluorobenzene is a polyhalo substituted benzene. It undergoes Suzuki coupling with 2-cyanoarylboronic esters to form the corresponding biphenyls. These biphenyls are the precursors for synthesizing 6-substituted phenanthridines. The enthalpy of vaporization at boiling point (467.15K) of 1-bromo-4-chloro-2-fluorobenzene is 40.737kjoule/mol.

1-Bromo-4-chloro-2-fluorobenzene(1996-29-8)Related Product Information

• BCDMH
• Chlorobromoisocyanurate
• 4-Bromofluorobenzene
• 5-Bromo-3-chloro-2-fluorophenylboronic acid
• 1-Bromo-2-chloro-4-fluorobenzene
• 4-Bromo-1-chloro-2-fluorobenzene
• 1,2-DIFLUORO-4,5-DIMETHOXYBENZENE
• 2-BROMO-1-CHLORO-4-FLUOROBENZENE,1-BROMO-2-CHLORO-5-FLUOROBENZENE,2-Bromo-1-chloro-4-fluorobenzene, 98+%,2-Bromo-1-chloro-4-fluorobenzene99%
• Bromine
• Bromochloromethane
• 1-BROMO-4-CHLORO-2,3,5,6-TETRAFLUOROBENZENE
• 5-CHLORO-2,3-DIBROMO-1-FLUOROBENZENE
• 1-BROMO-4-CHLORO-2-FLUORO-5-METHOXY-BENZENE
• Difluorochloromethane
• 4-Bromo-2-chloro-1-fluorobenzene
• 6-Bromo-3-chloro-2-fluorophenylboronic acid
• 2-BROMO-4-CHLORO-6-FLUOROANISOLE
• 1-Bromo-3-chloro-5-fluorobenzene98%,3-BROMO-5-CHLORO-1-FLUOROBENZENE,1-BROMO-3-CHLORO-5-FLUOROBENZENE