Basic information Safety Supplier Related

IRL-1620

Basic information Safety Supplier Related

IRL-1620 Basic information

Product Name:
IRL-1620
Synonyms:
  • IRL-1620, HUMAN
  • IRL-1620
  • ENDOTHELIN-1(8-21), N-SUC-[GLU9, ALA11,15]
  • N-SUC-[GLU9, ALA11,15]ENDOTHELIN-I (8-21)
  • N-SUCCINYL-[GLU9, ALA11,15]-ENDOTHELIN, 8-21
  • SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP
  • SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
  • SUCCINYL-(GLU9,ALA11,15)-ENDOTHELIN-1 (8-21)
CAS:
142569-99-1
MF:
C86H117N17O27
MW:
1820.95
Product Categories:
  • Endothelin receptor
Mol File:
142569-99-1.mol
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IRL-1620 Chemical Properties

Boiling point:
2096.6±65.0 °C(Predicted)
Density 
1.347±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
powder
pka
3.39±0.10(Predicted)
color 
white
Water Solubility 
Soluble in water (0.5 mg/ml)
Sequence
Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH
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Safety Information

WGK Germany 
3

MSDS

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IRL-1620 Usage And Synthesis

Biological Activity

IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM.

in vitro

IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900).

target

IC50: 16 pM (Endothelin receptor B), 19 μM (Endothelin receptor A)

storage

-20°C (desiccate)

IRL-1620Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Email
ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
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IRL-1620(142569-99-1)Related Product Information