IRL-1620
IRL-1620 Basic information
- Product Name:
- IRL-1620
- Synonyms:
-
- IRL-1620, HUMAN
- IRL-1620
- ENDOTHELIN-1(8-21), N-SUC-[GLU9, ALA11,15]
- N-SUC-[GLU9, ALA11,15]ENDOTHELIN-I (8-21)
- N-SUCCINYL-[GLU9, ALA11,15]-ENDOTHELIN, 8-21
- SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP
- SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
- SUCCINYL-(GLU9,ALA11,15)-ENDOTHELIN-1 (8-21)
- CAS:
- 142569-99-1
- MF:
- C86H117N17O27
- MW:
- 1820.95
- Product Categories:
-
- Endothelin receptor
- Mol File:
- 142569-99-1.mol
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IRL-1620 Chemical Properties
- Boiling point:
- 2096.6±65.0 °C(Predicted)
- Density
- 1.347±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- form
- powder
- pka
- 3.39±0.10(Predicted)
- color
- white
- Water Solubility
- Soluble in water (0.5 mg/ml)
- Sequence
- Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH
MSDS
- Language:English Provider:SigmaAldrich
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IRL-1620 Usage And Synthesis
Biological Activity
IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM.
in vitro
IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900).
target
IC50: 16 pM (Endothelin receptor B), 19 μM (Endothelin receptor A)
storage
-20°C (desiccate)
IRL-1620Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky(shanghai)International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
NCE Biomedical Co.,Ltd.
- Tel
- 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
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IRL-1620(142569-99-1)Related Product Information
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- DERMASEPTIN PHYLLOMEDUSA SAUVAGII
- Succinyl Coenzyme A, Lithium Salt
- ENDOTHELIN (16-21)
- CEGABA
- IRL-1620
- IRL 1620, [125I]-