DERMASEPTIN PHYLLOMEDUSA SAUVAGII Chemical Properties

storage temp. 

−20°C

solubility 

Soluble in DMSO

form 

Lyophilized powder

color 

White to off-white

Sequence

H-Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln-OH

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

DERMASEPTIN PHYLLOMEDUSA SAUVAGII Usage And Synthesis

Biological Activity

Dermaseptin is a polypeptide isolated from frog skin that exhibits potent antimicrobial activity against bacteria, fungi and protozoa.

in vitro

Dermaseptin is a water-soluble, thermostable, and nonhemolytic peptide endowed with highly potent antimicrobial activity against pathogenic fungi at micromolar concentration.

Source

Dermaseptin is derived from insect antimicrobial peptides; mammalian antimicrobial peptides; amphibian antimicrobial peptides; fish, mollusk and crustacean derived antimicrobial peptides; plant antimicrobial peptides and bacterial antimicrobial peptides.

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