Dodecylbenzenesulfonyl azide
Dodecylbenzenesulfonyl azide Basic information
- Product Name:
- Dodecylbenzenesulfonyl azide
- Synonyms:
-
- Dodecylbenzenesulfonyl Azide (soft type) (mixture)
- 4-Dodecylbenzenesulfonyl azide(soft type)(mixture)
- 4-DODECYLBENZENESULFONYL AZIDE
- 4-dodecylbenzensulfonyl azide
- Dodecylbenzenesulfonyl azide (soft type)
- P-DODECYLBENZENESULFONYL AZIDE OR 4-DODECYLBENZENESULFONYL AZIDE
- softtype
- P-DODECYLBENZENESULFONYL AZIDE
- CAS:
- 79791-38-1
- MF:
- C18H29N3O2S
- MW:
- 351.51
- EINECS:
- 679-864-1
- Mol File:
- 79791-38-1.mol
Dodecylbenzenesulfonyl azide Chemical Properties
- Density
- 1.051 g/mL at 25 °C
- refractive index
- n20/D1.510
- Flash point:
- >110℃
- solubility
- solubility pentane, acetone, and most organic solvents.
- form
- viscous liquid.
- color
- Light yellow to Brown
- CAS DataBase Reference
- 79791-38-1(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 10-36/37/38-20/22
- Safety Statements
- 16-36/37/39-26
- RIDADR
- 1993
- WGK Germany
- 3
- HS Code
- 29350090
Dodecylbenzenesulfonyl azide Usage And Synthesis
Uses
diazo-transfer reagent for activated methylene groups.
Uses
Reactant or reagent for synthesis of:
- Positron emission tomography ligand for imaging metabotropic glutamate receptor type 1
- Stitching agent for introduction of aziridines into functionalized organic molecules
- Parenteral cephalosporins
Reagent for:
- Intermolecular metal-catalyzed carbenoid cyclopropanations
- Solid-phase synthesis of indolecarboxylates using palladium catalyzed reactions
- Solid-phase rhodium carbenoid N-H insertion reactions
Uses
4-Dodecylbenzensulfonyl Azide is useful for the synthesis of N-(Benzo[h]quinolin-10-yl)-4-dodecylbenzenesulfonamide. Also, it is used in the preparation of ruthenium nanoparticles protected by ruthenium-nitrene n bonds.
Preparation
prepared by addition of granular sodium azide (1.3 equiv) to a mixture of isomeric sulfonyl chlorides (from a commercial mixture of isomers of p-dodecylbenzenesulfonic acid) in acetone solution.
Reactions
Reagent for Diazo-function Transfer.
The title reagent has been called a safer diazo-transfer reagent, and is a mixture of 12 or more isomeric p-dodecylbenzenesulfonyl azides, ranging by HPLC from 24% to 1% in area and giving essentially a single spot by TLC.
The title reagent has been shown to be very useful for the synthesis of various crystalline diazocarbonyl compounds such as diazobarbituric and diazoisopropylidenemalonic acids, derivatives and homologs of diazoacetoacetic acid, and 9-diazoanthrone (eq 1).
Formation of noncrystalline byproduct dodecylsulfonamides facilitates the workup procedure and isolation of the target crys- talline diazo compounds from the reaction mixture.
storage
Dodecylbenzenesulfonyl azide is the safest of the usual are nesulfonyl azides (tosyl azide, etc.) employed in diazo-transfer processes;appropriate care should be taken,as with all azides. Use in a fume hood.
Purification Methods
elution through short column containing silica gel G with methylene chloride-hexane (1:4) as eluant.
Dodecylbenzenesulfonyl azide Supplier
- Tel
- 0370-2059268 17530790913
- 3628320093@qq.com
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
- Tel
- 021-61259108 18621169109
- market03@meryer.com
- Tel
- +86 351 7031519
- sales@RHFChem.com
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
Dodecylbenzenesulfonyl azide (79791-38-1)Related Product Information
- SULFURYL FLUORIDE
- Phenylmethylsulfonyl fluoride
- Sulfosulfuron
- Chlorosulfonyl isocyanate
- Tosylmethyl isocyanide
- METHANESULFONYL HYDRAZIDE
- Trifluoroacetic acid
- Titanium tetrachloride
- 4-N-BUTYLBENZENESULFONAMIDE
- Tosyl azide
- Sodium azide
- Fibroblast Growth Factor 2 (basic), Rabbit anti-Human
- Azide
- Dodecylbenzenesulfonyl azide