Basic information Safety Supplier Related

AMAROGENTIN

Basic information Safety Supplier Related

AMAROGENTIN Basic information

Product Name:
AMAROGENTIN
Synonyms:
  • (4aS)-6α-[2-O-[(3,3',5-Trihydroxy-1,1'-biphenyl-2-yl)carbonyl]-β-D-glucopyranosyloxy]-5β-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one
  • Amarogentin from Gentia lutea
  • Amarogentin, 98%, from Gentiana scabra Bunge
  • Amarogentin Hydrate
  • AMAROGENTIN
  • 1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-4,4a,5,6-tetrahydro-6-[[2-O-[(3,3',5-trihydroxy[1,1'-biphenyl]-2-yl)carbonyl]-β-D-glucopyranosyl]oxy]-, (4aS,5R,6S)-
  • (2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate
  • (2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate
CAS:
21018-84-8
MF:
C29H30O13
MW:
586.54
Mol File:
21018-84-8.mol
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AMAROGENTIN Chemical Properties

Melting point:
229-230° (monohydrate)
alpha 
D20 -116.6° (methanol)
Boiling point:
928.5±65.0 °C(Predicted)
Density 
1.59±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 1 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form 
A crystalline solid
pka
7.42±0.40(Predicted)
color 
White to off-white
LogP
2.503 (est)
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AMAROGENTIN Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dry roots and rhizomes of Gentiana Gentiana scabra Bge.

Uses

Amarogentin has the functions of protecting liver and gallbladder, inhibiting bacteria and diuretic.

Definition

ChEBI: Amarogentin is a secoiridoid glycoside that consists of (4aS,5R,6R)-5-ethenyl-6-hydroxy-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one having a 2-O-[(3,3',5-trihydroxybiphenyl-2-yl)carbonyl]-beta-D-glucopyranosyl group attached at position 6 via a glycosidic linkage. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a metabolite. It is a secoiridoid glycoside and a monosaccharide derivative.

target

TargetValue
TAS2R1
()
TNF-α
()
AMPK
()

AMAROGENTINSupplier

Shaanxi Kebele Pharmaceutical R&D Co., Ltd Gold
Tel
13119135307 13119135307
Email
3866620171@qq.com
Naturewill Biotechnology Co., Ltd. Gold
Tel
18113192475 18113192475
Email
3157321941@qq.com
Chengdu Push Bio-Technology Co., Ltd. Gold
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Email
cwb1@biopurify.cn
Shanghai Winherb Medical Technology Co., Ltd.
Tel
400-400-186-5138 13341702378
Email
winherb@126.com
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