Basic information Safety Supplier Related

AMAROGENTIN

Basic information Safety Supplier Related

AMAROGENTIN Basic information

Product Name:
AMAROGENTIN
Synonyms:
  • (4aS)-6α-[2-O-[(3,3',5-Trihydroxy-1,1'-biphenyl-2-yl)carbonyl]-β-D-glucopyranosyloxy]-5β-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one
  • Amarogentin from Gentia lutea
  • Amarogentin, 98%, from Gentiana scabra Bunge
  • Amarogentin Hydrate
  • AMAROGENTIN
  • 1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-4,4a,5,6-tetrahydro-6-[[2-O-[(3,3',5-trihydroxy[1,1'-biphenyl]-2-yl)carbonyl]-β-D-glucopyranosyl]oxy]-, (4aS,5R,6S)-
  • (2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate
  • (2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate
CAS:
21018-84-8
MF:
C29H30O13
MW:
586.54
Mol File:
21018-84-8.mol
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AMAROGENTIN Chemical Properties

Melting point:
229-230° (monohydrate)
alpha 
D20 -116.6° (methanol)
Boiling point:
928.5±65.0 °C(Predicted)
Density 
1.59±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 1 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form 
A crystalline solid
pka
7.42±0.40(Predicted)
LogP
2.503 (est)
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AMAROGENTIN Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dry roots and rhizomes of Gentiana Gentiana scabra Bge.

Uses

Amarogentin has the functions of protecting liver and gallbladder, inhibiting bacteria and diuretic.

Definition

ChEBI: Amarogentin is a secoiridoid glycoside that consists of (4aS,5R,6R)-5-ethenyl-6-hydroxy-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one having a 2-O-[(3,3',5-trihydroxybiphenyl-2-yl)carbonyl]-beta-D-glucopyranosyl group attached at position 6 via a glycosidic linkage. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a metabolite. It is a secoiridoid glycoside and a monosaccharide derivative.

target

TargetValue
TAS2R1
()
TNF-α
()
AMPK
()

AMAROGENTINSupplier

Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Email
cwb1@biopurify.cn
Shanghai Winherb Medical Technology Co., Ltd.
Tel
400-1865138 13341702378
Email
190129269@qq.com
Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Tel
025-84430028 13815430202
Email
sale02@cqherb.com
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Email
marketing@targetmol.com
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AMAROGENTIN(21018-84-8)Related Product Information