Valtrate
Valtrate Basic information
- Product Name:
- Valtrate
- Synonyms:
-
- HalazuchroMe B
- ValepotriatuM
- ValtratuM
- VALTRATE(P)
- [(1S,6S,7aS)-4-(Acetyloxymethyl)-1-(3-methylbutanoyloxy)spiro[6,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-oxirane]-6-yl] 3-methylbutanoate
- Valtrate
- (1S,7R)-4-Acetoxymethyl-6,7aα-dihydrospiro[cyclopenta[c]pyran-7(1H),2'-oxirane]-1α,6α-diol 1,6-bis(3-methylbutanoate)
- VALTRATE(P)(PLEASE CALL)
- CAS:
- 18296-44-1
- MF:
- C22H30O8
- MW:
- 422.47
- EINECS:
- 242-174-2
- Product Categories:
-
- Miscellaneous Natural Products
- Mol File:
- 18296-44-1.mol
Valtrate Chemical Properties
- Boiling point:
- 525.9±50.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly, Sonicated), Methanol (Slightly)
- form
- Oil
- color
- Pale Brown to Dark Yellow
- Water Solubility
- slightly soluble in water
Valtrate Usage And Synthesis
Chemical Properties
Yellow liquid, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from spider lily and valerian.
Uses
Valtrate is a Rev-transport inhibitor with anti-HIV activity from Valerianae Radix.
Definition
ChEBI: Valtratum is a fatty acid ester.
in vivo
Valepotriate?showed significant anti-epileptic activity against MES- and PTZ-induced epilepsy at doses of 5, 10, and 20 mg/kg, and ED50?values for MES- and PTZ-induced epilepsy were 7.84 and 7.19 mg/kg, respectively. Furthermore,?valepotriate?(10 and 20 mg/kg) can significantly prolong sleeping time and shorten the latency time on the pentobarbital sodium-induced sleeping time test. Furthermore,?valepotriate?(5, 10, and 20 mg/kg) could significantly up-regulate the expression of GABAA, GAD65, and Bcl-2 and down-regulate the expression of caspase-3, but had no significant effect on the expression of GABAB[2].
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Valtrate(18296-44-1)Related Product Information
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