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Benzyloxyacetyl chloride

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Benzyloxyacetyl chloride Basic information

Product Name:
Benzyloxyacetyl chloride
Synonyms:
  • BENZYLOXYACETYL CHLORIDE
  • 2-(Benzyloxy)acetyl chloride
  • oxyacetyL
  • Benzyloxyacetyl chloride ,95%
  • (Benzyloxy)acetic acid chloride
  • 2-(Benzyloxy)acetic acid chloride
  • Benzyloxyacetic acid chloride
  • Acetyl chloride, 2-(phenylMethoxy)-
CAS:
19810-31-2
MF:
C9H9ClO2
MW:
184.62
EINECS:
629-534-8
Product Categories:
  • Acid Halides
  • Building Blocks
  • Organic Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • Carboxylic
  • Acid Halides
  • Carbonyl Compounds
  • Pyridines
Mol File:
19810-31-2.mol
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Benzyloxyacetyl chloride Chemical Properties

Melting point:
120 °C (decomp)
Boiling point:
84-87 °C/0.4 mmHg (lit.)
Density 
1.17 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.523(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
form 
Powder or Cyrstals
color 
White
Water Solubility 
Reacts with water.
Sensitive 
Moisture Sensitive
BRN 
1947363
CAS DataBase Reference
19810-31-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C
Risk Statements 
14-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
10-19
HazardClass 
8
PackingGroup 
III
HS Code 
29189900

MSDS

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Benzyloxyacetyl chloride Usage And Synthesis

Chemical Properties

Colorless to yellow liquid

Uses

Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.

Uses

Commonly employed reagent for asymmetric synthesis of β-lactams.1,2

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