Benzyloxyacetyl chloride Chemical Properties

Melting point:

120 °C (decomp)

Boiling point:

84-87 °C/0.4 mmHg (lit.)

Density 

1.17 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.523(lit.)

Flash point:

>230 °F

storage temp. 

2-8°C

form 

Powder or Cyrstals

color 

White

Water Solubility 

Reacts with water.

Sensitive 

Moisture Sensitive

BRN 

1947363

InChI

InChI=1S/C9H9ClO2/c10-9(11)7-12-6-8-4-2-1-3-5-8/h1-5H,6-7H2

InChIKey

QISAUDWTBBNJIR-UHFFFAOYSA-N

SMILES

C(Cl)(COCC1=CC=CC=C1)=O

CAS DataBase Reference

19810-31-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

14-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

10-19

HazardClass 

8

PackingGroup 

III

HS Code 

29189900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Benzyloxyacetyl chloride Usage And Synthesis

Chemical Properties

Colorless to yellow liquid

Uses

Benzyloxyacetyl chloride is a reagent used to construct substituted 2-azetidinones for further elaboration into annulated β-lactams. It is a commonly employed reagent for asymmetric synthesis of β-lactams. It is also used in preparation of (S)-3-(methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile, key intermediate in the preparation of fluoroquinolone antibiotic for respiratory tract infections, non-racemic helicene and β-lactams.

Uses

Commonly employed reagent for asymmetric synthesis of β-lactams.1,2

Benzyloxyacetyl chloride(19810-31-2)Related Product Information

• Trichloroacetyl chloride
• 4-Methoxybenzylchloride
• Sodium chloride
• Choline chloride
• Phenoxyacetyl chloride
• Ammonium chloride
• Calcium chloride
• Potassium chloride
• Thionyl chloride
• Oxalyl chloride
• Zinc chloride
• Chloroacetyl chloride
• Acetyl chloride
• Phenylacetyl chloride
• Bromoacetyl chloride
• Acetoxyacetyl chloride
• BENZYLOXYACETALDEHYDE
• 2-Chloroethyl ethyl ether