BETA-NAADP SODIUM SALT Chemical Properties

storage temp. 

-20°C

form 

Powder

color 

White to off-white

Water Solubility 

Soluble to 50 mM in water

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

BETA-NAADP SODIUM SALT Usage And Synthesis

Uses

NAADP Tetrasodium Salt is a Ca2+ mobilizing agent.

Uses

Nicotinic acid adenine dinucleotide phosphate sodium salt has been used for agonist injection into unfertilized eggs and embryos.

General Description

NAADP induces Ca²⁺?release from the eggs of sea urchin, when injected into the cell. It can be enzymatically produced from nicotinamide adenine dinucleotide phosphate (β-NADP) with the help of ADP-ribosyl cyclase.

Biological Activity

Ca 2+ mobilizing agent. Initiates Ca 2+ release via type 1 ryanodine receptor (RyR1) activation. Also regulates Ca 2+ release from intracellular stores distinct from the endoplasmic reticulum (ER); displays affinity for two-pore channels (TPCs) which release Ca 2+ from acidic organelles.

Biochem/physiol Actions

Potent activator of intracellular Ca2+ release via an IP3 and cyclic ADP ribose-independent mechanism.

BETA-NAADP SODIUM SALT(5502-96-5)Related Product Information

• NAADP-AM
• NAD+
• β-Nicotinamide Mononucleotide
• Adenine
• Triphosphopyridine nucleotide
• NADP, K
• BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE RESIN
• NADP, Disodium Salt
• NADP sodium salt
• BETA-NAADP SODIUM SALT
• NADP MONOPOTASSIUM SALT
• ALPHA-NADP SODIUM SALT
• β-Nicotinamide adenine dinucleotide phosphate sodium salt
• Nicotinic Acid Adenine Dinucleotide Phosphate