SODIUM TRICHLOROACETATE Chemical Properties

Melting point:

300 °C

Density 

0.9 g/cm3

storage temp. 

Sealed in dry,Room Temperature

form 

Powder or Granular Powder

pka

0.6[at 20 ℃]

color 

White to off-white

Water Solubility 

Soluble in water, ethanol, methanol, acetone.

Sensitive 

Hygroscopic

Merck 

14,9627

BRN 

3572664

InChIKey

SAQSTQBVENFSKT-UHFFFAOYSA-M

LogP

-2.67 at 25℃

CAS DataBase Reference

650-51-1(CAS DataBase Reference)

EPA Substance Registry System

Sodium trichloroacetate (650-51-1)

Safety Information

Hazard Codes 

Xi,N

Risk Statements 

37-50/53

Safety Statements 

46-60-61

RIDADR 

UN 3077 9/PG 3

WGK Germany 

2

RTECS 

AJ9100000

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29154000

Hazardous Substances Data

650-51-1(Hazardous Substances Data)

Toxicity

LD50 orl-rat: 3320 mg/kg KSKZAN 18(3),46,80

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

SODIUM TRICHLOROACETATE Usage And Synthesis

Chemical Properties

White to almost white powder

Uses

As a decalcifier and fixative in microscopy; also as a precipitant of protein. As herbicide.

Uses

Sodium trichloroacetate, is used in acid binding reagent in the textile industry in the dying process. Sodium trichloroacetate has been reported previously to be an effective denaturation reagent for proteins was applied to poly(l-lysine) and poly(l-glutamic acid) to see its effects on a coil-to-helix transition and on the chemical reactivities of the ε-amino group of poly(l-lysine). Addition of sodium trichloroacetate to poly-(l-lysine) induced a helical conformation even at neutral pH where the ε-amino group of the polymer was protonated.

Uses

Sodium trichloroacetate with trichloroacetic acid (TCA) undergoes rapid decarboxylation in dimethylformamide (DMF) in the presence of aldehydes to form nucleophilic trichloromethyl anion, which then adds to the aldehydes to form trichloromethyl carbinols. It can also undergo thermal decarboxylation in aprotonic solvents in the presence of olefins to generate dichlorocarbene as an intermediate.

Definition

ChEBI: TCA-sodium is an organic molecular entity.

Hazard

Toxic by ingestion, irritant to skin and eyes.

Flammability and Explosibility

Non flammable

Safety Profile

Moderately toxic by ingestion andintravenous routes. Human mutation data reported. Largedoses cause central nervous system depression. Used as anherbicide. Bags of the salt can ignite spontaneously instorage. When heated to decomposition it emits very

SODIUM TRICHLOROACETATE(650-51-1)Related Product Information

• Sodium acetate trihydrate
• Trichloroacetic acid
• Triclosan
• Hexane
• Trichloroisocyanuric acid
• Phenol
• Hydrazine sulfate
• Ethyl trichloroacetate
• Trichloroacetonitrile
• Sodium chlorate
• Chloroacetic acid
• Sodium chloroacetate
• Sodium dichloroacetate
• SODIUM TRICHLOROACETATE
• Dichloroacetic acid
• Dichloroacetate
• SODIUM TRICHLOROACETATE (TRICHLOROACETIC ACID SODIUM SALT)