Ethyl trichloroacetate Chemical Properties

Melting point:

237 °C

Boiling point:

168 °C (lit.)

Density 

1.378 g/mL at 25 °C (lit.)

vapor pressure 

2.34hPa at 25℃

refractive index 

n20/D 1.453(lit.)

Flash point:

149 °F

storage temp. 

Store below +30°C.

solubility 

alcohol: miscible(lit.)

form 

clear liquid

color 

Colorless to Almost colorless

Water Solubility 

immiscible

Merck 

14,9627

BRN 

1761567

Dielectric constant

7.8（20℃）

LogP

2.22 at 25℃

CAS DataBase Reference

515-84-4(CAS DataBase Reference)

NIST Chemistry Reference

Acetic acid, trichloro-, ethyl ester(515-84-4)

EPA Substance Registry System

Acetic acid, trichloro-, ethyl ester (515-84-4)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38

Safety Statements 

26-37/39-24/25

RIDADR 

2810

WGK Germany 

1

HS Code 

29154000

MSDS

• Language:English Provider:Ethyl trichloroacetate
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Ethyl trichloroacetate Usage And Synthesis

Chemical Properties

Colorless liquid with a menthol-like odor. It is miscible with ethanol, ether and benzene, but insoluble in water.

Uses

Ethyl trichloroacetate was used in the synthesis of dichlorocarbon precursor, phenyl(trichloromethyl)methyl.

Preparation

Ethyl trichloroacetate is synthesized from trichloroacetic acid and ethyl alcohol by the esterification reaction.
synthesis steps: Trichloroacetic acid(TCA), anhydrous ethyl alcohol and sulfuric acid are heated together and refluxed for 6 h. After cooling, the ester layer is separated by pouring into water, neutralized with 5-10% sodium carbonate solution, washed with water and dried overnight with anhydrous calcium chloride. After filtration, distillation was carried out to obtain the finished product. Yield 75%.

Application

Ethyl trichloroacetate can be used as solvent, organic synthesis, perfume and pharmaceutical intermediates.

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 3519, 1981 DOI: 10.1021/jo00330a028

General Description

Ethyl trichloroacetate undergoes atom-transfer radical addition reaction with styrene catalyzed by the Ru-pentamethylcyclopentadienyl complexes.

Purification Methods

Shake the ester with saturated aqueous Na2CO3 (three times), aqueous 50% CaCl2 (three times), saturated aqueous NaCl (twice), then distil over CaCl2 and redistil it under reduced pressure. [Beilstein 2 IV 514.]

Ethyl trichloroacetate(515-84-4)Related Product Information

• Tris(2-chloroethyl) phosphate
• Ethyl chloroacetate
• Ethyl acrylate
• Ethyl bromoacetate
• Ethyl acetate
• Ethylparaben
• ACETIC ACID 2-CHLOROETHYL ESTER
• Ethyl cyanoacetate
• Ethyl propiolate
• Ethanol
• Trinexapac-ethyl
• ISOXADIFEN-ETHYL
• Ethyl phenylacetate
• ETHYL DICHLOROACETATE
• 2,2,2-TRICHLOROETHYL ACETATE
• Trichloroethanol
• Chloroacetic acid
• TRICHLOROACETIC ANHYDRIDE