N,N-Diethylethylenediamine Chemical Properties

Melting point:

<-70°C

Boiling point:

145-147 °C(lit.)

Density 

0.827 g/mL at 25 °C(lit.)

vapor pressure 

5.33hPa at 20℃

refractive index 

n20/D 1.436(lit.)

Flash point:

87 °F

storage temp. 

Store below +30°C.

solubility 

soluble in Methanol, Water

form 

Liquid

pka

pK1:7.70(+2);pK2:10.46(+1) (25°C)

color 

Clear colorless to light yellow

explosive limit

0.7-8.4%(V)

Water Solubility 

MISCIBLE

Sensitive 

Air Sensitive

BRN 

605299

InChIKey

PQZTVWVYCLIIJY-UHFFFAOYSA-N

LogP

0.1 at 25℃

CAS DataBase Reference

100-36-7(CAS DataBase Reference)

NIST Chemistry Reference

1,2-Ethanediamine, N,N-diethyl-(100-36-7)

EPA Substance Registry System

N,N-Diethylethylenediamine (100-36-7)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

10-20/21/22-35-21-36/37/38-34

Safety Statements 

26-36/37/39-45-25-16-36-27

RIDADR 

UN 2685 8/PG 2

WGK Germany 

1

RTECS 

KV3500000

Autoignition Temperature

245 °C

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29212900

Toxicity

LD50 orally in Rabbit: 984 mg/kg LD50 dermal Rabbit 820 mg/kg

MSDS

• Language:English Provider:2-Aminoethyldiethylamine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

N,N-Diethylethylenediamine Usage And Synthesis

Chemical Properties

CLEAR COLORLESS TO LIGHT YELLOW LIQUID

Uses

N,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. It is also used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.

Uses

N,N-Diethylethylenediamine is used in the syntheses of anti-malarials. In addition, it has been seem to induce apoptosis through a caspase-3 dependent pathway.

Flammability and Explosibility

Flammable

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion and skin contact. A slun and severe eye irritant. Flammable liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.

Toxics Screening Level

The initital threshold screening level (ITSL) for 2-diethylaminoethylamine is 9 μg/m3 based on an annual averaging time.

N,N-Diethylethylenediamine(100-36-7)Related Product Information

• N-(1-Naphthyl)ethylenediamine dihydrochloride
• Diethyl oxalate
• 2-(2-Aminoethylamino)ethanol
• Mefenpyr-diethyl
• Ethylene glycol diethyl ether
• 2-Aminoethyldiisopropylamine
• 2-Aminoethyl(ethyl)amine
• N,N-Dimethylethylenediamine
• 2-Aminoethylammonium chloride
• N,N,N',N'-Tetramethylethylenediamine
• Diethyl malonate
• N,N'-Diisopropylcarbodiimide
• Methyl 4-acetamido-5-bromo-2-methoxybenzoate
• 4-AMINO-5-BROMO-2-METHOXYBENZENECARBOXYLIC ACID
• 4-(acetylamino)-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
• N,N-Diethylhydroxylamine
• 2-Cyano-N,N-diethylacetamide
• N,N-Dimethylacetoacetamide