4-HYDROXYPHENOXYACETIC ACID Chemical Properties

Melting point:

154-157 °C (lit.)

Boiling point:

372.6±17.0 °C(Predicted)

Density 

1.367±0.06 g/cm3(Predicted)

solubility 

soluble in Methanol

form 

Fine Crystalline Powder

pka

3.27±0.10(Predicted)

color 

Off-white to beige

BRN 

1952779

LogP

0.650

CAS DataBase Reference

1878-84-8(CAS DataBase Reference)

EPA Substance Registry System

Acetic acid, (4-hydroxyphenoxy)- (1878-84-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HS Code 

29189990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-HYDROXYPHENOXYACETIC ACID Usage And Synthesis

Chemical Properties

off-white to beige fine crystalline powder

Uses

2-(4-Hydroxyphenoxy)acetic Acid is used in the design, synthesis and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Acts as a reagent in the preparation, anti-HIV and kinesin Eg5 inhibitory activities, QSAR, and modeling studies of triazolothiadiazole and triazolothiadiazine derivatives. Synthesis of thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties.

Definition

ChEBI: 4-Hydroxypheoxyacetate is a monocarboxylic acid.

General Description

(4-Hydroxyphenoxy)acetic acid along with formaldehyde ammonium salt forms a polyaromatic anionic compound RG-13577. RG-13577 mimics the synthetic heparin and specifically binds to the vascular smooth muscle cells (SMCs) and inhibits their proliferative growth. In the molecules of (4-hydroxyphenoxy)acetic acid, the carboxyl groups are held together by R₂²(8) hydrogen bonds.

4-HYDROXYPHENOXYACETIC ACID(1878-84-8)Related Product Information

• 4-BENZYLOXYPHENOXYACETIC ACID
• Quizalofop-p-ethyl
• Trolox
• Diclofop
• 4-HYDROXYPHENOXYACETIC ACID
• 4-Methoxyphenoxyacetic acid
• Diclofop-methyl
• HYDROQUINONE-O,O'-DIACETIC ACID
• Haloxyfop-etotyl
• 4-O-(Carboxymethyl)rifamycin
• 4-(TRIFLUOROMETHOXY)PHENOXYACETIC ACID
• 2-HYDROXYPHENOXYACETIC ACID,2-Hydroxyphenoxyacetic acid, 98+%
• Phenoxyacetic acid
• 4-ACETOXYPHENOXYACETIC ACID
• 2-(4-HYDROXYPHENOXY)PROPIONIC ACID
• 3,5-DIBROMO-4-HYDROXYPHENOXYACETIC ACID
• DICLOFOP METHYL, 5-HYDROXY
• DL-2-[4-(TRIFLUOROMETHOXY)PHENOXY]PROPIONIC ACID