Basic information Safety Supplier Related

Disitamab

Basic information Safety Supplier Related

Disitamab Basic information

Product Name:
Disitamab
Synonyms:
  • Disitamab
  • Research Grade Disitamab (DHC09603)
  • Research Grade Disitamab
  • Disitamab (anti-ERBB2)
CAS:
2185868-98-6
MW:
0
Mol File:
Mol File
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Disitamab Chemical Properties

form 
Liquid
color 
Colorless to light yellow
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Disitamab Usage And Synthesis

Uses

Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (Disitamab vedotin (HY-P9985))[1].

in vivo

Disitamab (27 mg/kg; i.v.; once; 5 mL/kg) shows no significant toxicity in monkeys[1].

IC 50

HER2

References

[1] Jiang J, et al. Preclinical safety profile of disitamab vedotin：a novel anti-HER2 antibody conjugated with MMAE. Toxicol Lett. 2020;324:30-37. DOI:10.1016/j.toxlet.2019.12.027

DisitamabSupplier

Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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3008007409@qq.com
Wuhan Chemstan Biotechnology Co., Ltd.
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027-65317797 15926423062
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422450190@qq.com
TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
Biolab Reagents
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027-65279366 18108604356
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products@biolabreagent.com
Wuhan Jingkangen Biomedical Technology Co., Ltd
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13720134139 086-15871494362 13720134139
Email
orders@jknbiochem.com
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Disitamab(2185868-98-6)Related Product Information