ChemicalBook > CAS DataBase List > Disitamab
Disitamab
- Product Name
- Disitamab
- CAS No.
- 2185868-98-6
- Chemical Name
- Disitamab
- Synonyms
- Disitamab;Disitamab (anti-ERBB2);Research Grade Disitamab;Research Grade Disitamab (DHC09603)
- CBNumber
- CB18081154
- Formula Weight
- 0
- MOL File
- Mol file
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Disitamab Property
- form
- Liquid
- color
- Colorless to light yellow
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Disitamab Chemical Properties,Usage,Production
Uses
Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (Disitamab vedotin (HY-P9985))[1].
in vivo
Disitamab (27 mg/kg; i.v.; once; 5 mL/kg) shows no significant toxicity in monkeys[1].
IC 50
HER2
References
[1] Jiang J, et al. Preclinical safety profile of disitamab vedotin:a novel anti-HER2 antibody conjugated with MMAE. Toxicol Lett. 2020;324:30-37. DOI:10.1016/j.toxlet.2019.12.027
Disitamab Preparation Products And Raw materials
Raw materials
Preparation Products
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Disitamab Suppliers
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