ChemicalBook > CAS DataBase List > Disitamab

Disitamab

Product Name
Disitamab
CAS No.
2185868-98-6
Chemical Name
Disitamab
Synonyms
Disitamab;Disitamab (anti-ERBB2);Research Grade Disitamab;Research Grade Disitamab (DHC09603)
CBNumber
CB18081154
Formula Weight
0
MOL File
Mol file
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Disitamab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Disitamab Chemical Properties,Usage,Production

Uses

Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (Disitamab vedotin (HY-P9985))[1].

in vivo

Disitamab (27 mg/kg; i.v.; once; 5 mL/kg) shows no significant toxicity in monkeys[1].

IC 50

HER2

References

[1] Jiang J, et al. Preclinical safety profile of disitamab vedotin:a novel anti-HER2 antibody conjugated with MMAE. Toxicol Lett. 2020;324:30-37. DOI:10.1016/j.toxlet.2019.12.027

Disitamab Preparation Products And Raw materials

Raw materials

Preparation Products

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Disitamab Suppliers

Wuhan Maixi Biotechnology Co., Ltd
Tel
027-65523427 18007167883
Email
Service@mabnus.com
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China
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906
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Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
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3008007409@qq.com
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China
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89689
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Wuhan Chemstan Biotechnology Co., Ltd.
Tel
027-65317797 15926423062
Fax
QQ:422450190
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422450190@qq.com
Country
China
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10308
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24960
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58
Biolab Reagents
Tel
027-65279366 18108604356
Email
products@biolabreagent.com
Country
China
ProdList
9866
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Wuhan Jingkangen Biomedical Technology Co., Ltd
Tel
13720134139 086-15871494362 13720134139
Email
orders@jknbiochem.com
Country
China
ProdList
7062
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58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
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China
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11972
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Wuhan Acumen Bio-Technology Co.,ltd
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027-027-16602739303 16602739303
Email
673003916@qq.com
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China
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4117
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Shanghai jerryxing Biomedical Technology Co., Ltd
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17721492509 17721492509
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460170712@qq.com
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China
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4894
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Changsha Fuzhen Biotechnology Co.,LTD
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18229892877 13823398779
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3062105966@qq.com
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China
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5350
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