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ChlorproMazine Sulfoxide

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ChlorproMazine Sulfoxide Basic information

Product Name:
ChlorproMazine Sulfoxide
Synonyms:
  • Chlorpromazine-S-oxide
  • 3-(2-chloro-5-keto-phenothiazin-10-yl)propyl-dimethyl-amine
  • 3-(2-chloro-5-oxo-phenothiazin-10-yl)-N,N-dimethyl-propan-1-amine
  • 3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
  • Chlorpromazine impurity 1/Chlorpromazine EP Impurity A/Chlorpromazine Sulfoxide/2-Chloro-N,N-dimethyl-10H-Phenothiazine-10-propanamine 5-Oxide
  • 10H-Phenothiazine-10-propanamine,2-chloro-N,N-dimethyl-, 5-oxide
  • 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1- amine S-oxide
  • Chlorpromazine EP impurity A
CAS:
969-99-3
MF:
C17H19ClN2OS
MW:
334.86
Product Categories:
  • Amines, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Mol File:
969-99-3.mol
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ChlorproMazine Sulfoxide Chemical Properties

Melting point:
115°
Boiling point:
502.6±50.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator, Under Inert Atmosphere
solubility 
Chloroform (Sparingly), Methanol (Slightly)
pka
pKa 9.0 (Uncertain)
color 
Off-White to Brown
InChIKey
QEPPAOXKZOTMPM-UHFFFAOYSA-N
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Safety Information

RIDADR 
UN 2811 6.1 / PGIII
Toxicity
LD50 s.c. in mice: 102 mg/kg (Minami, Yoshimoto)
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ChlorproMazine Sulfoxide Usage And Synthesis

Uses

Chlorpromazine Sulfoxide is a derivative of Chlorpromazine Hydrochloride (C424750), which is a dopamine antagonist of the typical antipsychotic class of medications possessing additional antiadrenergic, antiserotonergic, anticholinergic and antihistaminergic properties used for schizophrenia treatment.

Definition

ChEBI: 3-(2-chloro-5-oxo-10-phenothiazinyl)-N,N-dimethyl-1-propanamine is a member of phenothiazines.

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