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C18 CERAMIDE

Basic information Safety Supplier Related

C18 CERAMIDE Basic information

Product Name:
C18 CERAMIDE
Synonyms:
  • D-ERYTHRO-SPHINGOSINE, N-STEAROYL-
  • D-ERYTHRO-SPHINGOSINE, N-STEAROYLDIHYDRO
  • C18 CERAMIDE
  • C18-D-ERYTHRO-CERAMIDE
  • C18 DIHYDROCERAMIDE
  • C18 DIHYDROSPHINGOSINE
  • 18:0 CERAMIDE
  • (2S, 3R)-2-STEAROYLAMINOOCTADECANE-1,3-DIOL
CAS:
2304-81-6
MF:
C36H71NO3
MW:
565.95
Product Categories:
  • Mixed Fatty Acids
  • Activators
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Protein Kinase Inhibitors and Activators
Mol File:
2304-81-6.mol
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C18 CERAMIDE Chemical Properties

Melting point:
99-101 °C
alpha 
[α]D20 -2～-5゜ (c=0.5, CHCl3)
Boiling point:
630.97°C (rough estimate)
Density 
0.9512 (rough estimate)
refractive index 
1.6630 (estimate)
storage temp. 
−20°C
solubility 
Chloroform (Slightly, Heated, Sonicated), Methanol (Sparingly)
pka
13.54±0.20(Predicted)
form 
White to off-white powder.
color 
White to Off-White
BRN 
1717539
Stability:
Stable, but may be heat sensitive - store below 4 ℃. Incompatible with strong oxidizing agents.
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29225000

MSDS

  • Language:English Provider:ACROS
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C18 CERAMIDE Usage And Synthesis

Chemical Properties

Off White Powder

Uses

The sphingolipid ceramide is a potent inhibitor of the mitochondrial permeability transition pore.

Definition

ChEBI: N-octadecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl). It has a role as a mouse metabolite. It is a N-acylsphingosine and a N-stearoyl-sphingoid base. It is functionally related to an octadecanoic acid.

Biological Activity

C18 Ceramide based derivatives are present in low levels during neurodegeneration. It favors endoplasmic reticulum based stress and autophagy in glioma cells. Low levels of C18-ceramide are implicated in human head and neck squamous cell carcinoma. C18 ceramide may inhibit tumor progression.

C18 CERAMIDESupplier

Shanghai Renshi Pharmatech Co., LTD Gold
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021-61150625 17721318029
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info@renshipharma.com
Guangzhou Aiyu Technology Co.,Ltd Gold
Tel
18588406486
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courage.you@foxmail.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
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jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
Email
market03@meryer.com
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
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