C18 CERAMIDE
C18 CERAMIDE Basic information
- Product Name:
- C18 CERAMIDE
- Synonyms:
-
- D-ERYTHRO-SPHINGOSINE, N-STEAROYL-
- D-ERYTHRO-SPHINGOSINE, N-STEAROYLDIHYDRO
- C18 CERAMIDE
- C18-D-ERYTHRO-CERAMIDE
- C18 DIHYDROCERAMIDE
- C18 DIHYDROSPHINGOSINE
- 18:0 CERAMIDE
- (2S, 3R)-2-STEAROYLAMINOOCTADECANE-1,3-DIOL
- CAS:
- 2304-81-6
- MF:
- C36H71NO3
- MW:
- 565.95
- Product Categories:
-
- Mixed Fatty Acids
- Activators
- Fatty Acid Derivatives & Lipids
- Glycerols
- Protein Kinase Inhibitors and Activators
- Mol File:
- 2304-81-6.mol
C18 CERAMIDE Chemical Properties
- Melting point:
- 99-101 °C
- alpha
- [α]D20 -2～-5゜ (c=0.5, CHCl3)
- Boiling point:
- 630.97°C (rough estimate)
- Density
- 0.9512 (rough estimate)
- refractive index
- 1.6630 (estimate)
- storage temp.
- −20°C
- solubility
- Chloroform (Slightly, Heated, Sonicated), Methanol (Sparingly)
- pka
- 13.54±0.20(Predicted)
- form
- White to off-white powder.
- color
- White to Off-White
- BRN
- 1717539
- Stability:
- Stable, but may be heat sensitive - store below 4 ℃. Incompatible with strong oxidizing agents.
- InChIKey
- VODZWWMEJITOND-NXCSZAMKSA-N
- SMILES
- C(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)(=O)CCCCCCCCCCCCCCCCC
Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29225000
MSDS
- Language:English Provider:ACROS
C18 CERAMIDE Usage And Synthesis
Chemical Properties
Off White Powder
Uses
The sphingolipid ceramide is a potent inhibitor of the mitochondrial permeability transition pore.
Definition
ChEBI: N-octadecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl). It has a role as a mouse metabolite. It is a N-acylsphingosine and a N-stearoyl-sphingoid base. It is functionally related to an octadecanoic acid.
Biological Activity
C18 Ceramide based derivatives are present in low levels during neurodegeneration. It favors endoplasmic reticulum based stress and autophagy in glioma cells. Low levels of C18-ceramide are implicated in human head and neck squamous cell carcinoma. C18 ceramide may inhibit tumor progression.
in vivo
In the rat Kainate injury model, C18-Ceramide has an increasing content in the brain after injury. C18-Ceramide might facilitate the exocytosis of glutamate from damaged neurons, thus propagating neuronal injury[1].
C18 CERAMIDESupplier
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- 021-61150625 17721318029
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- Tel
- 13564401937
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- Tel
- 18210857532; 18210857532
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- 4006356688 18621169109
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- 821-50328103-801 18930552037
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C18 CERAMIDE(2304-81-6)Related Product Information
- N-OCTADECANOYLSPHING-OSYLPHOSPHORYLCHOLINE
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- C18 CERAMIDE
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- A-GALACTOSYL-C18-CERAMIDE
- D-ERYTHRO-SPHINGOSINE
- CERAMIDE TRIHEXOSIDES, [GALACTOSE-6-3H]
- (2S,3R,4E)-N-TETRACOSANOYL SPHINGOSINE
- IGB3
- KRN7000
- GALACTOSYL CERAMIDE, [GALACTOSE-6-3H]
- C18-D-ERYTHRO-SPHINGOSINE
- N-OCTANOYL-D-ERYTHRO-DIHYDROSPHINGOSINE [4,5-3H] 1-PHOSPHATE
- α-Galactosyl-C18-ceramide
- B-GALACTOSYL-C18-CERAMIDE
- C18-L-THREO-CERAMIDE
- CEREBROSIDES WITH C18-D35 FATTY ACID SIDE CHAIN
- BETA-D-GALACTOPYRANOSYL(1-4)-BETA-D-GLUCOPYRANOSYL CERAMIDE