BILIVERDIN DIHYDROCHLORIDE Chemical Properties

RTECS 

DU3033000

storage temp. 

-20°C

solubility 

Soluble in DMSO, DMF, and basic aqueous solutions

form 

Powder

Sensitive 

Light Sensitive

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

WGK Germany 

3

BILIVERDIN DIHYDROCHLORIDE Usage And Synthesis

Uses

Biliverdin dihydrochloride was found responsible for cytoprotection. It was also found to induce tolerance to cardiac allografts. Biliverdin hydrochloride may regulate the cellular heme degradation process by occupying the heme binding site on heme oxygenase which would prevent access of the substrate to the catalytic site of the enzyme.

General Description

Biliverdin?(BV) is considered as a near-infrared (NIR)-absorbing pigment, that is endogenic. It is a linear tetrapyrrolic intermediate of heme degradation (heme catabolism) to bilirubin. The bile of amphibia and birds contains only biliverdine, no bilirubin.

Biochem/physiol Actions

Biliverdin (BV) is an excellent anti-inflammatory agent that protects against lipopolysaccharides (LPS)-induced lung injury in mouse endothelial cells. It aids protection in polymicrobial sepsis. Biliverdin has cytoprotective effects on rat livers and protects from prolonged ischemia and reperfusion injury. It also shows antioxidant activities.

BILIVERDIN DIHYDROCHLORIDE(55482-27-4)Related Product Information

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