1-METHYLINDOLE-3-ACETAMIDE Chemical Properties

Melting point:

181 °C

Boiling point:

440.4±28.0 °C(Predicted)

Density 

1.20±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

pka

16.22±0.40(Predicted)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

HazardClass 

IRRITANT

1-METHYLINDOLE-3-ACETAMIDE Usage And Synthesis

Uses

2-(1-Methyl-1H-indol-3-yl)acetamide, is a building block used in various chemical synthesis such as in preparation of anilino-monoindolylmaleimides as selective JAK3 inhibitors with selectivity over JAK2 and TYK2 for potential treatment of rheumatoid arthritis.

1-METHYLINDOLE-3-ACETAMIDE(150114-41-3)Related Product Information

• GF109203X
• RO-31-8220
• 2-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-3-(1H-INDOL-3-YL)MALEIMIDE, HCL
• N-(4-ACETAMIDOPHENYL)-1-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETAMIDE
• N-(2-PHENYLETHYL)-1-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETAMIDE
• N-(3-PYRIDYL)-1-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETAMIDE
• 3-(4-BROMOPHENYL)-5-(1-METHYLINDOL-3-YL)-1H,4H,5H-1,2-DIAZIN-6-ONE
• 1-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-2-MORPHOLINO-1,2-ETHANEDIONE
• N'-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-N'-METHYL-2-OXOACETOHYDRAZIDE
• 3-(4-CYCLOHEXYLPHENYL)-5-(1-METHYLINDOL-3-YL)-1H,4H,5H-1,2-DIAZIN-6-ONE
• 3-(4-ETHOXYPHENYL)-5-(1-METHYLINDOL-3-YL)-1H,4H,5H-1,2-DIAZIN-6-ONE
• 4-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-1,2-DIHYDRO-3H-PYRAZOL-3-ONE
• 2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-N-[(METHOXYAMINO)METHYLENE]ACETAMIDE
• rim 1
• 2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-2-OXOACETAMIDE
• 3-(4-(TERT-BUTYL)PHENYL)-5-(1-METHYLINDOL-3-YL)-1H,4H,5H-1,2-DIAZIN-6-ONE
• 2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-N-(2-(4-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]PIPERAZINO)ETHYL)-2-OXOACETAMIDE
• 1-[4-(4-CHLOROPHENYL)PIPERAZINO]-2-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-INDOL-3-YL)-1,2-ETHANEDIONE