3-Dimethylaminopropane-1,2-diol Chemical Properties

Boiling point:

216-217 °C(lit.)

Density 

1.004 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.4609(lit.)

Flash point:

221 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

clear liquid

pka

14.13±0.20(Predicted)

Specific Gravity

1.001.004

color 

Colorless to Light yellow

Stability:

Stable. Incompatible with oxidizing agents, acids.

InChI

InChI=1S/C5H13NO2/c1-6(2)3-5(8)4-7/h5,7-8H,3-4H2,1-2H3

InChIKey

QCMHUGYTOGXZIW-UHFFFAOYSA-N

SMILES

C(O)C(O)CN(C)C

CAS DataBase Reference

623-57-4(CAS DataBase Reference)

NIST Chemistry Reference

1,2-Propanediol, 3-(dimethylamino)-(623-57-4)

EPA Substance Registry System

1,2-Propanediol, 3-(dimethylamino)- (623-57-4)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

23-26-27-36/37/39-45

RIDADR 

UN 3267 8/PG 2

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

HS Code 

2922190090

MSDS

• Language:English Provider:3-(Dimethylamino)-1,2-propanediol
• Language:English Provider:SigmaAldrich

3-Dimethylaminopropane-1,2-diol Usage And Synthesis

Chemical Properties

pale yellow solid

Uses

3-(Dimethylamino)-1,2-propanediol was used in the preparation of:

• synthetic cationic lipid, N-[1-(2,3-dioleyloxy)propyl-N,N,N-trimethylammonium chloride (DOTMA), used in DNA-transfection protocol
• indane-derived bis(oxazolines)

3-Dimethylaminopropane-1,2-diol(623-57-4)Related Product Information

• 3-Amino-1,2-propanediol
• 3-Dimethylaminopropylamine
• 1-Methoxy-2-propyl acetate
• Propylene glycol
• 1-Methoxy-2-propanol
• 2-METHYL-1,3-PROPANEDIOL
• N,N-Dimethyl-1,4-phenylenediamine
• 1,3-Propanediol
• (R)-(-)-1,2-Propanediol
• DI(PROPYLENE GLYCOL) BUTYL ETHER
• 2,2-Dimethyl-1,3-propanediol
• 2,2'-Cyclouridine
• 4-THIOURIDINE
• 3-(Diethylamino)-1,2-propanediol
• Uridine 5′-monophosphate disodium salt
• Riboflavin
• 5-Azacytidine
• 5-Bromouridine