2,2'-Cyclouridine Chemical Properties

Melting point:

248-251 °C(lit.)

alpha 

-21°(19℃, c=4, H2O)

Boiling point:

456.3±55.0 °C(Predicted)

Density 

2.01±0.1 g/cm3(Predicted)

refractive index 

-20 ° (C=4, H2O)

storage temp. 

-20°C

solubility 

DMSO:2.0(Max Conc. mg/mL);8.84(Max Conc. mM)
PBS (pH:7.2):1.0(Max Conc. mg/mL);4.42(Max Conc. mM)

pka

12.55±0.40(Predicted)

form 

powder to crystal

color 

White to Almost white

optical activity

[α]19/D 21°, c = 4 in H2O

InChI

InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1

InChIKey

UUGITDASWNOAGG-CCXZUQQUSA-N

SMILES

C12O[C@@]3([H])[C@H](O)[C@@H](CO)O[C@@]3([H])N1C=CC(=O)N=2

CAS DataBase Reference

3736-77-4

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

2,2'-Cyclouridine Usage And Synthesis

Description

2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil is a research tool for anticancer and antiviral studies. This works by inhibiting uridine phosphorylase, a key enzyme targeted by some antitumor drugs.

Chemical Properties

White powder

Uses

O2,2''-Cyclouridine is a research tool for anticancer and antiviral studies.

Uses

Research tool for antiviral and anticancer studies.1

2,2'-Cyclouridine(3736-77-4)Related Product Information

• Doxifluridine
• 1-beta-D-Arabinofuranosyluracil
• Floxuridine
• Trifluridine
• Uridine
• 3-ETHOXY-1,2-PROPANEDIOL
• (2R,4R)-(-)-PENTANEDIOL
• 1,3-Dimethoxybutane
• 2-ISOPROPOXYETHANOL
• N-(2-METHOXYETHYL)METHYLAMINE
• 3-Dimethylaminopropane-1,2-diol
• (S)-(+)-1-Methoxy-2-propanol
• 1,2-Dimethoxypropane
• Diethylene glycol monomethyl ether
• 4-Methoxy-1-butanol
• 2,2'-Anhydro-5-methyluridine
• (S)-(+)-1-Amino-2-propanol
• (R)-(-)-1-METHOXY-2-PROPANOL