(S)-(+)-1-Methoxy-2-propanol Chemical Properties

Melting point:

-84.2°C (estimate)

Boiling point:

118-119 °C

alpha 

20 º (c=10, CHCl3)

Density 

0.921 g/mL at 20 °C (lit.)

refractive index 

n20/D 1.403

Flash point:

33 °C

storage temp. 

Sealed in dry,2-8°C

solubility 

Chloroform (Sparingly), Methanol (Slightly)

pka

14.49±0.20(Predicted)

form 

Liquid

color 

Clear colorless

optical activity

[α]20/D +22±2°, c = 10% in chloroform

BRN 

1718940

Stability:

Volatile

InChIKey

ARXJGSRGQADJSQ-BYPYZUCNSA-N

CAS DataBase Reference

26550-55-0

Safety Information

Hazard Codes 

F

Risk Statements 

10-15

Safety Statements 

24-43-7/8-16

RIDADR 

UN 3092 3/PG 3

WGK Germany 

3

HazardClass 

3

PackingGroup 

Ⅲ

HS Code 

29094990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

(S)-(+)-1-Methoxy-2-propanol Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

(S)-(+)-1-Methoxy-2-propanol can be used as a reactant to prepare:

• (S)-1-methoxypropan-2-yl 4-methylbenzenesulfonate by reacting with tosyl chloride in the presence of pyridine.
• Thiazolopyridine urea derivatives.
• Quinazoline derivatives as potential inhibitors of EGFR/HER-2 tyrosine kinases.

Purification Methods

Wash the ethers with aqueous NaHCO3 in the presence of solid NaCl, dry them with MgSO4 and fractionally distil them. The RS-acetate [108-65-6] M 132.2 has b 145-146o/atm. The R(+) and S(-) enantiomers have [] D ±20.5o (c 10, H2O). [Beilstein 1 II 536, 1 III 2146, 1 IV 2471.]

(S)-(+)-1-Methoxy-2-propanol(26550-55-0)Related Product Information

• POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE
• p-Anisidine
• m-Anisyl alcohol
• 2-Methoxyethanol
• Anisole
• (Trifluoromethoxy)benzene
• Isopropyl alcohol
• Methoxyacetone
• Methoxyacetic acid
• p-Anisaldehyde
• 1-Propanol
• 1,1,1-TRIFLUORO-2,3-EPOXYPROPANE
• R-(+)-2-TRIFLUOROMETHYLOXIRANE
• Clofibrate
• 1-Methoxy-2-propanol
• 2,2'-Cyclouridine
• 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
• D-RIBULOSE