R-(+)-2-TRIFLUOROMETHYLOXIRANE Chemical Properties

Boiling point:

25-32 °C

Density 

1.294 g/mL at 25 °C

refractive index 

n20/D <1.300

Flash point:

-15 °F

storage temp. 

2-8°C

form 

liquid

color 

Clear

Safety Information

Hazard Codes 

F+

Risk Statements 

12

Safety Statements 

3

RIDADR 

UN 1993 3/PG 1

WGK Germany 

3

HS Code 

2910900090

R-(+)-2-TRIFLUOROMETHYLOXIRANE Usage And Synthesis

Uses

(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane can be used as a substrate to synthesize:

• Substituted trifluoro amino propanols, which are found to be potent inhibitors of cholesteryl ester transfer protein.
• (2R) Trifluoro-(methoxybenzyloxy)-propanol (chiral glycol) by reacting with 4-methoxybenzyl alcohol in the presence of NaH. Chiral glycol intermediate is further utilized for the preparation of trifluoromethyl glycol carbamates as potential monoacylglycerol lipase (MAGL) inhibitors.

R-(+)-2-TRIFLUOROMETHYLOXIRANE(143142-90-9)Related Product Information

• 1,1,1-TRIFLUORO-2,3-EPOXYPROPANE
• ETHYLENE OXIDE
• (S)-(+)-1-Methoxy-2-propanol
• 2-(HEPTAFLUOROPROPOXY)TETRAFLUOROPROPIONYL FLUORIDE
• POLY(PERFLUOROPROPYLENE OXIDE)
• R-(+)-2-TRIFLUOROMETHYLOXIRANE
• Epifluorohydrin
• 2,2-BIS(TRIFLUOROMETHYL)OXIRANE
• 2,2-DIFLUORO-3,3-BIS(TRIFLUOROMETHYL)OXIRANE