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Epifluorohydrin

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Epifluorohydrin Basic information

Product Name:
Epifluorohydrin
Synonyms:
  • (fluoromethyl)oxirane
  • 1,2-epoxy-3-fluoro-propan
  • 1-fluoro-2,3-epoxypropane
  • 2-(Fluoromethyl)oxirane
  • 3-Fluoropropene-1,2-oxide
  • Epifluorhydrine
  • Propane, 1,2-epoxy-3-fluoro-
  • 3-Fluoro-1,2-propenoxide 99%
CAS:
503-09-3
MF:
C3H5FO
MW:
76.07
EINECS:
207-960-1
Product Categories:
  • Contact Printing
  • Fluorine-Containing Monomers for 157 nm UV Lithography Resist Polymers
  • Lithography Monomers
  • Self Assembly &amp
  • Building Blocks
  • Chemical Synthesis
  • Epoxides
  • Fluorinated Building Blocks
  • Heterocyclic Fluorinated Building Blocks
  • Materials Science
  • Micro/NanoElectronics
  • Organic Building Blocks
  • Other Fluorinated Heterocycles
  • Oxygen Compounds
  • monomer
Mol File:
503-09-3.mol
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Epifluorohydrin Chemical Properties

Boiling point:
85-86 °C (lit.)
Density 
1.067 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.368(lit.)
Flash point:
40 °F
storage temp. 
0-6°C
form 
liquid
color 
clear
CAS DataBase Reference
503-09-3(CAS DataBase Reference)
NIST Chemistry Reference
Oxirane, (fluoromethyl)-(503-09-3)
EPA Substance Registry System
Epifluorohydrin (503-09-3)
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-34
Safety Statements 
16-26-45-38-36/37/39-33
RIDADR 
UN 2924 3/PG 2
WGK Germany 
3
RTECS 
TZ3325000
Hazard Note 
Flammable/Highly Toxic
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
2910900090

MSDS

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Epifluorohydrin Usage And Synthesis

Chemical Properties

clear colourless liquid

Uses

Epifluorohydrin is used as a reagent in the synthesis of N-arylphosphoramidates. In addition, it is used in the synthesis of orally bioavailable ALK inhibitors in the treatment of tumors.

General Description

Clear colorless liquid.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

A halogenated epoxide. Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts. The chlorinated derivative has been shown to be incompatible with aniline, strong oxidizers, sulfuric acid, isopropylamine, zinc, aluminum, iron, etc. see epichlorohydrin.

Health Hazard

ACUTE/CHRONIC HAZARDS: Epifluorohydrin is a lacrimator. When heated to decomposition it emits toxic fumes.

Fire Hazard

Epifluorohydrin is flammable.

EpifluorohydrinSupplier

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