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Sunitinib N-Oxide

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Sunitinib N-Oxide Basic information

Product Name:
Sunitinib N-Oxide
Synonyms:
  • Sunitinib N-Oxide
  • DNCVCKYIYMUMFC-ATVHPVEESA-N
  • (Z)-N,N-diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethanamine oxide
  • Sunitinib Impurity 6
  • 1H-?Pyrrole-?3-?carboxamide, N-?[2-?(diethyloxidoamino)?ethyl]?-?5-?[(Z)?-?(5-?fluoro-?1,?2-?dihydro-?2-?oxo-?3H-?indol-?3-?ylidene)?methyl]?-?2,?4-?dimethyl
  • Sunitinib N-O
  • Sunitinib N-oxide/(Z)-N,N-Diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethan-1-amine oxide
  • (Z)-N,N-diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethan-1-amine oxide
CAS:
356068-99-0
MF:
C22H27FN4O3
MW:
414.47
Mol File:
356068-99-0.mol
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Sunitinib N-Oxide Chemical Properties

Melting point:
>155°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
11.69±0.20(Predicted)
form 
Solid
color 
Yellow to Dark Orange
Stability:
Hygroscopic
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Sunitinib N-Oxide Usage And Synthesis

Uses

Sunitinib N-Oxide, is a derivative of Sunitinib (S820000), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK), used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor. It is a COVID19-related research product.

Sunitinib N-OxideSupplier

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