Cholesteryl oleate Chemical Properties

Melting point:

44-47 °C (lit.)

Boiling point:

617.95°C (rough estimate)

Density 

0.9287 (rough estimate)

refractive index 

-20 ° (C=2, THF)

Flash point:

>230 °F

storage temp. 

-20°C

solubility 

chloroform: 0.1 g/mL, clear, colorless

form 

Solid

color 

White to Off-White

BRN 

2343071

LogP

18.284 (est)

CAS DataBase Reference

303-43-5(CAS DataBase Reference)

NIST Chemistry Reference

Cholesteryl oleate(303-43-5)

EPA Substance Registry System

Cholest-5-en-3-ol (3.beta.)-, (9Z)-9-octadecenoate (303-43-5)

Safety Information

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

MSDS

• Language:English Provider:Oleic acid cholesteryl ester
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Cholesteryl oleate Usage And Synthesis

Description

Cholesteryl oleate is a cholesterol ester. It has been used in the generation of nanoparticles and liposomes for drug delivery.

Chemical Properties

white to off-white powder, lumpy powder or pale

Uses

Cholesteryl oleate was used to study the ability of silicone hydrogel contact lenses to absorb tear lipids, cholesterol and cholesterol esters. It was also used in the development of amperometric cholesterol biosensors.

Definition

ChEBI: The (Z)-stereoisomer of cholesteryl octadec-9-enoate.

Biochem/physiol Actions

Cholesterol in plasma is present in an esterified form such as Cholesteryl oleate. The liver is a primary source of cholesteryl oleate that enriches the LDL particles when released into plasma. The secretion of lipoproteins enriched with cholesteryl oleate has close correlation with the pathogenesis of coronary artery atherosclerosis.

Purification Methods

Purify the oleate ester by chromatography on silica gel and eluting with MeOH. [Beilstein 6 III 2642.]

Cholesteryl oleate (303-43-5)Related Product Information

• TRIOLEIN
• POLYGLYCERYL-10 OLEATE
• Pentaerythrityl oleate
• Methyl Oleate
• Diethyl phthalate
• OLEYL OLEATE
• Polyethylene glycol monooleate
• Oleic acid
• Tris(trimethylsilyl)phosphate
• Glyceryl Monooleate
• [(3S,8S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] 2,4-dichlorobenzoate
• Dimethyl succinate
• Methyl acrylate
• Cholesteryl hemisuccinate
• Sodium oleate
• 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate
• nonyl octanoate
• DL-sec-Butyl acetate