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5-Hydroxymethylpyrrolidin-2-one

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5-Hydroxymethylpyrrolidin-2-one Basic information

Product Name:
5-Hydroxymethylpyrrolidin-2-one
Synonyms:
  • D-PYROGLUTAMINOL
  • (-)-D-PYROGLUTAMOL
  • (R)-5-HYDROXYMETHYL-PYRROLIDIN-2-ONE
  • (R)-(-)-5-(HYDROXYMETHYL)-2-PYRROLIDINONE
  • (R)-5-(HYDROXYMETHYL)-2-PYRROLIDINONE
  • (R)-(-)-5-(HYDROXYMETHYL)-2-PYRROLIDONE
  • (R)-(-)-2-PYRROLIDONE-5-YL-METHANOL
  • 5-(Hydroxymethyl)-2-pyrrolidinone
CAS:
66673-40-3
MF:
C5H9NO2
MW:
115.13
EINECS:
626-701-7
Product Categories:
  • Heterocycles
  • pharmacetical
  • Amino Acids 13C, 2H, 15N
  • Amides (Chiral)
  • Chiral Building Blocks
  • Synthetic Organic Chemistry
  • Amino Acids & Derivatives
  • Chiral Reagents
Mol File:
66673-40-3.mol
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5-Hydroxymethylpyrrolidin-2-one Chemical Properties

Melting point:
83-85 °C(lit.)
Boiling point:
147-149 °C0.06 mm Hg(lit.)
Density 
1.1808 (rough estimate)
refractive index 
-31 ° (C=5, EtOH)
Flash point:
147-149°C/0.06m
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform, Dimethylformamide, Water
form 
Crystalline Powder or Flakes
pka
14.35±0.10(Predicted)
color 
White to yellow
optical activity
[α]20/D 31°, c = 5 in ethanol
BRN 
5728422
CAS DataBase Reference
66673-40-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
3-10
HS Code 
29337900

MSDS

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5-Hydroxymethylpyrrolidin-2-one Usage And Synthesis

Chemical Properties

(R)-5-(Hydroxymethyl)-2-pyrrolidinone is White Powder

Uses

(R)-5-(Hydroxymethyl)-2-pyrrolidinone is a 2-pyrrolidone derivative for therapeutic use as prostanoid receptor agonist.

Uses

Serves as a building block in the synthesis of diphthamide.

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