Vibralactone D Chemical Properties

Melting point:

131-132 °C

Boiling point:

362.6±25.0 °C(Predicted)

Density 

1.150±0.06 g/cm3(Predicted)

pka

14.47±0.40(Predicted)

Vibralactone D Usage And Synthesis

Uses

Vibralactone D (Compound 1) is a metabolite isolated and cultured from natural basidiomycetes Boreostereum vibrans. Vibralactone D shows weak inhibitory activity against isoenzymes of 11b-hydroxysteroid dehydrogenase (HSD) (IC50 85.7 μM).

References

[1] Jiang MY, et al. Vibralactones D-F from cultures of the basidiomycete Boreostereum vibrans. Chem Pharm Bull (Tokyo). 2010 Jan;58(1):113-6. DOI:10.1248/cpb.58.113

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