ChemicalBook > Product Catalog > API > Digestive system drugs > Cholagogue Drugs > 2-Hydroxy-N-(4-hydroxyphenyl)-benzamide
2-Hydroxy-N-(4-hydroxyphenyl)-benzamide
2-Hydroxy-N-(4-hydroxyphenyl)-benzamide Basic information
- Product Name:
- 2-Hydroxy-N-(4-hydroxyphenyl)-benzamide
- Synonyms:
-
- LOIRD
- 2-hydroxy-n-(4-hydroxyphenyl)-benzamide
- 2-hydroxy-n-(4-hydroxyphenyl)-benzamid
- 4’-hydroxy-salicylanilid
- 4’-hydroxysalicylanilide
- 4-Hydroxysalicylanilide
- auxobil
- OSALMID
- CAS:
- 526-18-1
- MF:
- C13H11NO3
- MW:
- 229.23
- EINECS:
- 208-385-9
- Product Categories:
-
- john's
- Mol File:
- 526-18-1.mol
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2-Hydroxy-N-(4-hydroxyphenyl)-benzamide Chemical Properties
- Melting point:
- 179°
- Boiling point:
- 371.13°C (rough estimate)
- Density
- 1.2084 (rough estimate)
- vapor pressure
- 0Pa at 25℃
- refractive index
- 1.5500 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO : ≥ 28 mg/mL (122.15 mM)
- pka
- 8.40±0.30(Predicted)
- Water Solubility
- 916mg/L at 25℃
- LogP
- 2.47 at 25℃
- CAS DataBase Reference
- 526-18-1(CAS DataBase Reference)
- EPA Substance Registry System
- Osalmid (526-18-1)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-42/43
- Safety Statements
- 26-36/37
- Toxicity
- LD50 oral in rat: 6702mg/kg
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2-Hydroxy-N-(4-hydroxyphenyl)-benzamide Usage And Synthesis
Definition
ChEBI: Osalmid is an organic molecular entity.
Biochem/physiol Actions
Osalmid is a potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid inhibits RR (ribonucleotide reductase) activity in vivo, and exhibits synergistic effect with lamivudine on inactivation mutant HBV strain. Osalmid is a biliation activator (choleretic agent), but a mechanism of this activity remains unknown.
2-Hydroxy-N-(4-hydroxyphenyl)-benzamide Preparation Products And Raw materials
Raw materials
2-Hydroxy-N-(4-hydroxyphenyl)-benzamideSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
Shanghai Longsheng chemical Co.,Ltd.
- Tel
- 021-58099652-8005 13585536065
- bin.wu@shlschem.com
Shanghai Jin Yi Fine Chemical Co.,LTD
- Tel
- 021-52801082 13918092929
- jinyi_service@jyfinechem.com
Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel
- 0571-82693216
- info@yuhaochemical.com
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2-Hydroxy-N-(4-hydroxyphenyl)-benzamide(526-18-1)Related Product Information
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- 2-Hydroxy-N-(4-methoxyphenyl)-11H-benzo[a]carbazole-3-carboxamide
- Rafoxanide
- 2-Hydroxy-N-(4-hydroxyphenyl)-benzamide
- Salicylanilide
- 4'-ethoxysalicylanilide
- 4-hydroxy-N-(4-hydroxyphenyl)benzamide
- 4-hydroxy-N-(3-hydroxyphenyl)benzamide
- 3-hydroxy-N-(4-hydroxyphenyl)benzamide
- AURORA 3537
- N-(4-HYDROXYPHENYL)-2-METHOXYBENZAMIDE
- AURORA 3538
- AURORA 2063
- N,N-DIMETHYL(2-([4-(TRIFLUOROMETHOXY)ANILINO]CARBONYL)PHENYL)SULFAMATE
- AURORA 383