Sennoside B Chemical Properties

Melting point:

209～212℃

alpha 

D20 -100° (c = 0.2 in 70% acetone); D20 -67° (c = 0.4 in 70% dioxane)

Boiling point:

698.48°C (rough estimate)

Density 

1.3066 (rough estimate)

refractive index 

1.7630 (estimate)

storage temp. 

2-8°C

solubility 

DMSO (Very Slightly, Heated), Methanol (Slightly, Heated)

pka

3.31±0.40(Predicted)

color 

Light Yellow to Dark Yellow

BRN 

5723747

Stability:

Hygroscopic

LogP

1.880 (est)

CAS DataBase Reference

128-57-4(CAS DataBase Reference)

Safety Information

Risk Statements 

22

Safety Statements 

22-45-24/25

WGK Germany 

3

HS Code 

29329990

Sennoside B Usage And Synthesis

Chemical Properties

White to brown powder

Uses

Sennoside B is used in the inhibition of platelet driven growth factor (PDGF) used and may inhibit proliferative disease which depend upon the PDGF pathway. Laxative.

Definition

ChEBI: A member of the class of sennosides that is (9R,9'S)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'.

Purification Methods

Sennoside B forms yellow crystals from aqueous acetone or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3402.]

Sennoside B(128-57-4)Related Product Information

• CHLOROPHOSPHONAZO III
• Sennoside D
• SENNOSIDE A(SH),SENNOSIDE A(P),SENNOSIDE,CALCIUM SENNOSIDE 5%, 10%, 20%, 60%,Sennoside A std.,SENNOSIDE A hplc,SENNOSIDE A WITH HPLC,Sennoside A1,SENNOSIDE A
• Sennoside C
• SENNIDINE A
• 4-Acetylbenzoic acid
• 4-FORMYL-3-HYDROXYBENZOIC ACID
• 2,2'-DIHYDROXYBENZOPHENONE
• 3-Hydroxy-4-methylbenzoic acid
• 5-ISOPROPYL-3-METHYLPHENOL
• 4-BROMOBENZHYDROL
• BIANTHRONYL
• HELICIN
• 4-ETHYL-3-HYDROXYBENZOIC ACID
• 1,1,2,2-TETRAPHENYLETHANE
• SENNOSIDE A AND B,SENNOSIDE
• SENNOSIDES
• 2-METHOXY-2'-METHYLBENZOPHENONE