2-Hydroxypyrimidine Chemical Properties

Melting point:

177-178 °C(Solv: ethyl acetate (141-78-6))

Density 

1.28±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

pka

pK1:2.24(＋1);pK2:9.17(0) (25°C)

CAS DataBase Reference

557-01-7(CAS DataBase Reference)

NIST Chemistry Reference

2(1H)-Pyrimidinone(557-01-7)

EPA Substance Registry System

2(1H)-Pyrimidinone (557-01-7)

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-40

Safety Statements 

22-26-36

2-Hydroxypyrimidine Usage And Synthesis

Uses

Pyrimidin-2(5H)-one is a useful research chemical compound used in the preparation . of a palladium-containing metal-organic framework as a reusable catalyst for the Suzuki coupling of p-bromoanisole and phenylboronic acid.

Definition

ChEBI: Pyrimidin-2-ol is the hydroxypyrimidine that is pyrimidine mono-substituted at C-2 by a hydroxy group. It has a role as a Lewis base and an electron donor.

Purification Methods

It crystallises from EtOH or ethyl acetate. Its solubility in H2O at 20o is 1g/2.2mL. [Albert J Chem Soc 4219 1952, Beilstein 24 III/IV 194.]. 2-Hydroxypyrimidine hydrochloride [38353-09-2] M 132.5, has m 203-205.5o(dec)

2-Hydroxypyrimidine(557-01-7)Related Product Information

• Sulfadiazine
• Hydroxyapatite
• Hydroxy silicone oil
• Silver sulfadiazine
• Glycolic acid
• CYTIDINE 3'-MONOPHOSPHATE
• 5-METHYLCYTIDINE
• (+)-3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine
• 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
• 2'-Deoxycytidine hydrochloride
• N4-Acetylcytidine
• 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL
• 4-HYDROXYPYRIMIDINE 98%
• Cytidine
• 2-HYDROXYPYRIMIDINE HYDROCHLORIDE 99%
• 5-Hydroxypyrimidine
• 5-IODOCYTOSINE
• Camptothecin Series--10-hydroxycamptothecin