4-Hydroxypyrimidine Chemical Properties

Melting point:

166-169 °C(lit.)

Boiling point:

179.58°C (rough estimate)

Density 

1.2604 (rough estimate)

refractive index 

1.4610 (estimate)

storage temp. 

0-6°C

pka

pK1:1.85(＋1);pK2:8.59(0) (25°C)

form 

Powder

color 

White to slightly yellow

Water Solubility 

270.3g/L(20 ºC)

BRN 

106975

CAS DataBase Reference

51953-17-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-37/39-26-36

WGK Germany 

3

RTECS 

UW7350100

TSCA 

Yes

HS Code 

29339900

MSDS

• Language:English Provider:4-Hydroxypyrimidine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Hydroxypyrimidine Usage And Synthesis

Description

Pyrimidone(4-Hydroxypyrimidine) is the name given to either of two heterocyclic compounds with the formula C4H4N2O: 2-pyrimidone and 4-pyrimidone. The compounds can also be called 2-hydroxypyrimidine or 4-hydroxypyrimidine respectively, based on a substituted pyrimidine, or 1, 3-diazine, ring. 4-pyrimidinone is an important bioactive molecule with various biological activities such as anti-virus, anti-tumor, induction of interferon production and immune regulation.

Chemical Properties

white to slightly yellow powder

Hazard

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Enzyme inhibitor

This hygroscopic pyrimidine, also known as 4-hydroxypyrimidine and 4- pyrimidinol (FW = 96.09 g/mol), inhibits both hypoxanthine(guanine) and xanthine phosphoribosyltransferases.

4-Hydroxypyrimidine(51953-17-4)Related Product Information

• 4-Hydroxypyrimidine
• 2,2'-Anhydro-5-methyluridine
• DIHYDROFOLIC ACID
• L-Tetrahydrofolic Acid
• L-SEPIAPTERIN
• 6-METHYL-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE
• XANTHOPTERIN
• 2,3'-ANHYDROTHYMIDINE
• 2,2'-Cyclouridine
• 4,6-Dihydroxy-5-methoxypyrimidine
• 4(1H)-Pyrimidinone, 2-amino-6-(hydroxymethyl)- (9CI)
• 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol
• 6-CHLORO-4-HYDROXYPYRIMIDINE,98%
• 4,5-Dimethyl-2-pyrimidinol
• 2,4-Diamino-6-hydroxypyrimidine ,98%
• 4,5-DIMETHYL-2-(DIMETHYLAMINO)-6-HYDROXYPYRIMIDINE
• 4-Ethyl-5-fluoro-6-hydroxypyrimidine
• 5-Hydroxy-1,4-dihydropyrimidin-4-one