tert-Butyl 3-(methylamino)propylcarbamate Chemical Properties

Boiling point:

280.3±23.0 °C(Predicted)

Density 

0.949±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

12.82±0.46(Predicted)

Appearance

Colorless to light yellow Liquid

InChI

InChI=1S/C9H20N2O2/c1-9(2,3)13-8(12)11-7-5-6-10-4/h10H,5-7H2,1-4H3,(H,11,12)

InChIKey

YIMSPDZAVBIXRT-UHFFFAOYSA-N

SMILES

C(OC(C)(C)C)(=O)NCCCNC

Safety Information

HS Code 

2924297099

tert-Butyl 3-(methylamino)propylcarbamate Usage And Synthesis

Synthesis

The general procedure for the synthesis of tert-butyl 2-(methylamino)propylcarbamate using the compound (CAS:1158721-71-1) as starting material was as follows: compound 20 (12 g, 0.037 mol) was dissolved in 100 mL of methanol and 0.5 g of 5% Pd/C catalyst was added. The hydrogenation reaction was carried out at 60 psi hydrogen pressure for 45 minutes. Upon completion of the reaction, the catalyst was removed by filtration and the solvent was removed by distillation under reduced pressure to afford the target product tert-butyl 2-(methylamino)propylcarbamate as a colorless oil (6 g, 65% yield).

References

[1] Patent: US2009/137618, 2009, A1. Location in patent: Page/Page column 12-13

tert-Butyl 3-(methylamino)propylcarbamate(442514-22-9)Related Product Information

• tert-Butyl carbamate
• Methyl anthranilate
• Diisobutyl phthalate
• Dibutyl phthalate
• Buprofezin
• POLYURETHANE
• BUTYL OLEATE
• Cyhalofop-butyl
• tert-Butyl carbazate
• tert-Butyl glycinate
• tert-Butyl peroxybenzoate
• Urethane
• 4-Aminobenzoic acid
• Butyl formate
• tert-Butanol
• tert-Butyl 4-aminobenzoate
• Butyl acetate
• Diethylene glycol monobutyl ether