2-Cyanobenzaldehyde Chemical Properties

Melting point:

103-105 °C (lit.)

Boiling point:

284.9±23.0 °C(Predicted)

Density 

1.15±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMSO (Slightly, Sonicated), Chloroform (Slightly)

form 

Powder, Crystals and/or Chunks

color 

White to orange to beige

Sensitive 

Air Sensitive

CAS DataBase Reference

7468-67-9(CAS DataBase Reference)

NIST Chemistry Reference

2-Cyanobenzaldehyde(7468-67-9)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-37/39-36/37/39-36

RIDADR 

UN 3439 6.1/PG 3

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

6.1

PackingGroup 

III

HS Code 

29124990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2-Cyanobenzaldehyde Usage And Synthesis

Chemical Properties

white to orange to beige powder, crystals and/or

Uses

This compound can act as a crosslinker to protein kinase, which is responsible for thousands of phosphorylation events in the phosphoproteome.

Uses

2-Cyanobenzaldehyde may be used:

• in the base-catalyzed one-pot synthesis of 3-substituted isoindolinones
• in the synthesis of 3-oxo-2,3-dihydro-1H-isoindoles, via Baylis-Hillman reaction
• in the synthesis of 3-(N-substituted amino)-1-isoindolenones

General Description

Aldol addition of enolizable 1,3-dicarbonyl compounds to 2-cyanobenzaldehyde in the presence of a tertiary amine has been reported. Biotransformation of 2-cyanobenzaldehyde by Euglena gracilis Z cultured photohetero-trophically has been reported.

2-Cyanobenzaldehyde(7468-67-9)Related Product Information

• 4-Dimethylaminobenzaldehyde
• o-Anisaldehyde
• 3-(Trifluoromethyl)benzaldehyde
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• Benzaldehyde
• 2-Nitrobenzaldehyde
• 4-Hydroxybenzaldehyde
• p-Anisaldehyde
• 2-ACETYLBENZENECARBONITRILE
• 4-Cyanobenzaldehyde
• 2-CYANOBENZOIC ACID
• 2-CYANOBENZAMIDE
• METHYL 2-CYANOBENZOATE
• 2-Cyano-5-methoxybenzoic acid
• 2-Fluoro-5-Formylbenzonitrile/2-Fluoro-5-Cyanobenzaldehyde,4-Fluoro-3-cyanobenzaldehyde
• 2-FLUORO-4-CYANOBENZALDEHYDE
• α-Cyanobenzaldehyde oxime
• 3-CYANOBENZALDEHYDE 98+%,3-Cyanobenzaldehyde,97%,m-Cyanobenzaldehyde 3-Cyanobenzaldehyde,M-CYANOBENZALDEHYDE,3-CYANOBENZALDEHYDE