Cyclohexanecarboxaldehyde Chemical Properties

Melting point:

34-35°C

Boiling point:

161-163 °C (lit.)

Density 

0.926 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.452(lit.)

Flash point:

105 °F

storage temp. 

2-8°C

form 

Liquid

color 

Clear colorless to faintly pink

Water Solubility 

Soluble in chloroform, ether, alcohol. Slightly soluble in water.

Sensitive 

Air Sensitive

BRN 

878306

InChIKey

KVFDZFBHBWTVID-UHFFFAOYSA-N

LogP

1.900 (est)

CAS DataBase Reference

2043-61-0(CAS DataBase Reference)

NIST Chemistry Reference

Cyclohexanecarboxaldehyde(2043-61-0)

Safety Information

Hazard Codes 

Xi,F

Risk Statements 

10-36/37/38-36

Safety Statements 

16-26-36-37/39

RIDADR 

UN 1989 3/PG 3

WGK Germany 

3

F 

8-9-23

HazardClass 

3

PackingGroup 

III

HS Code 

29122990

MSDS

• Language:English Provider:Hexahydrobenzaldehyde
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Cyclohexanecarboxaldehyde Usage And Synthesis

Chemical Properties

Clear colorless to faintly pink liquid

Uses

Cyclohexanecarboxaldehyde was used to study gas-phase microwave spectrum of cyclohexanecarboxaldehyde. It was used for the synthesis of poly(vinyl cyclohexanal). It was used as model substrate in the synthesis of propargylamines using Fe₃O₄ nanoparticles as catalyst. It was employed in an aldol reaction with ethyl diazoacetate catalyzed by basic, nanoparticulate magnesium oxide leading to α-diazo-β-hydroxyesters.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 42, p. 1041, 1994 DOI: 10.1248/cpb.42.1041
Tetrahedron Letters, 24, p. 573, 1983 DOI: 10.1016/S0040-4039(00)81467-7

Synthesis

The prepared Grignard reagent was pressed into a dry and clean 20 L reaction bottle, the temperature of the Grignard reagent was cooled to -20° C. and controled at -10±5° C. then 1.506 g of dimethylformamide was dropwise added to the reaction bottle in about 2 h, the temperature of the system was preserved at a temperature below 0° C. for 2 h. 7 L of HCl having a concentration of 4 mol/L was dropwise added to the reaction bottle to terminate the reaction to obtain a reaction product. Suction filtration was performed for the reaction product, an obtained filtrate was standed to enable liquid separation, an obtained water phase was extracted twice with 2.8 L of EA, extracted organic phases were combined and washed with 3 L of saturated salt water, and concentration was performed to obtain 1.608 kg of Cyclohexanecarboxaldehyde having a purity of 96% and a yield of 83%.

Cyclohexanecarboxaldehyde(2043-61-0)Related Product Information

• Molasses
• Cyclohexylbenzene
• Isocyanatocyclohexane
• Methylcyclohexane
• Cyclohexanemethanol
• Chlorocyclohexane
• Ethylcyclohexane
• Cyclohexane
• Cyclohexanecarboxylic acid
• Cyclohexene oxide
• CYCLOHEXYL VINYL ETHER
• Cyclohexanecarbonitrile
• (Aminomethyl)cyclohexane
• 1,3-Cyclohexanedicarboxylic acid
• Ethyl trans-2-[4-(Boc-aMino)cyclohexyl]acetate
• Cyclohexanecarboxamide
• CYCLOHEXANE-1,1-DICARBOXYLIC ACID
• Cyclohexylboronic acid pinacol ester