1,3-Benzenedimethanol Chemical Properties

Melting point:

56-60 °C (lit.)

Boiling point:

154-159 °C/13 mmHg (lit.)

Density 

1.1610

refractive index 

1.5090 (estimate)

Flash point:

154-159°C/13mm

storage temp. 

Sealed in dry,Room Temperature

form 

Solution, may develop some turbidity precipitate

pka

13.98±0.10(Predicted)

color 

Clear to hazy colorless to yellow

Water Solubility 

Soluble in water.

BRN 

1562398

CAS DataBase Reference

626-18-6(CAS DataBase Reference)

EPA Substance Registry System

1,3-Benzenedimethanol (626-18-6)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/22-36-22

Safety Statements 

9-7-23-26

WGK Germany 

3

TSCA 

Yes

HS Code 

29062900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1,3-Benzenedimethanol Usage And Synthesis

Chemical Properties

WHITE CRYSTALLINE POWDER AND CHUNKS

Uses

1,3-Benzenedimethanol was used in the synthesis of a series of cross-linked poly(orthocarbonate)s. It was also used in the synthesis of mixed-tethered system, required for the preparation of e-edge-[60]fullerenylmethanodihydropyrrole adduct.

Synthesis

The general procedure for the synthesis of 1,3-benzenedimethanol from isophthalaldehyde was as follows: in a 25 mL round bottom flask equipped with a magnetic stirrer, an ethanol solution (5 mL) of isophthalaldehyde (1 mmol) was added. Subsequently, P(BVP)BH4 (100 mg) was added to the reaction system and the reaction was stirred at room temperature. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was filtered and washed sequentially with 1.0 M hydrochloric acid (2 × 10 mL) and ethanol (25 mL) to remove unreacted reagents. The filtrates were combined and concentrated under reduced pressure to give pure 1,3-benzenedimethanol in moderate to very high yields. For the few cases where the reaction is incomplete, the crude product needs to be purified by silica gel column chromatography using an appropriate eluent (see Scheme 1).

References

[1] Chemistry - A European Journal, 2013, vol. 19, # 24, p. 7701 - 7707
[2] Journal of Organic Chemistry, 2018, vol. 83, # 4, p. 2274 - 2281
[3] Comptes Rendus Chimie, 2013, vol. 16, # 8, p. 721 - 727
[4] Comptes Rendus Chimie, 2014, vol. 17, # 1, p. 23 - 29
[5] Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, 2003, vol. 42, # 4, p. 744 - 750

1,3-Benzenedimethanol(626-18-6)Related Product Information

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• Triphenylmethanol
• 4-Hydroxybenzyl alcohol
• Musk xylene
• m-Anisyl alcohol
• Diethylstilbestrol
• Benzhydrol
• Ethylene glycol diacetate
• Diethylene glycol
• Benzene
• PROPYLENE GLYCOL
• 1,2-BENZENEDIMETHANOL,O-BENZENEDIMETHANOL,1,2-BENZENEDIMETHANOL 97%,1,2-Benzenedimethanol,97%
• 1,2,4-Benzenetricarboxylic acid
• 1,2,3-Benzenetricarboxylic acid hydrate
• Trimesic acid