Basic information Safety Supplier Related

prolylglutamic acid

Basic information Safety Supplier Related

prolylglutamic acid Basic information

Product Name:
prolylglutamic acid
Synonyms:
  • prolylglutamic acid
  • L-Pro-L-Glu-OH
  • Pro-Glu-OH
  • Pro-Glu
  • (2S)-2-{[(2S)-pyrrolidin-2-yl]formamido}pentanedioic acid
  • L-Glutamic acid, L-prolyl-
  • (S)-2-((S)-Pyrrolidine-2-carboxamido)pentanedioic acid
CAS:
67644-00-2
MF:
C10H16N2O5
MW:
244.24
Mol File:
67644-00-2.mol
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prolylglutamic acid Chemical Properties

solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
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prolylglutamic acid Usage And Synthesis

Uses

H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway[1].

Definition

ChEBI: A dipeptide formed from L-proline and L-glutamic acid residues.

References

[1] Daleke MH, et al. Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway. J Biol Chem. 2011 May 27;286(21):19024-34. DOI:10.1074/jbc.M110.204966

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