H-PRO-HYP-OH Chemical Properties

Boiling point:

513.5±50.0 °C(Predicted)

Density 

1.417±0.06 g/cm3(Predicted)

storage temp. 

-15°C

solubility 

Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

2.98±0.40(Predicted)

color 

White to Off-White

Stability:

Hygroscopic

H-PRO-HYP-OH Usage And Synthesis

Chemical Properties

White powder

Uses

H-Pro-Hyp-OH is a collagen peptide composed of proline (Pro) and hydroxyproline (Hyp). H-Pro-Hyp-OH can be used in research on slowing down facial aging[1].

Definition

ChEBI: Pro-Hyp is a dipeptide composed of L-proline and L-hydroxyproline residues. It is a biomarker for bone collagen degradation. It has a role as a diagnostic agent, a human metabolite and a biomarker. It is functionally related to a L-proline and a trans-4-hydroxy-L-proline. It is a tautomer of a Pro-Hyp zwitterion.

References

[1] Tedesco L, et al. A designer mixture of six amino acids promotes the extracellular matrix gene expression in cultured human fibroblasts. Biosci Biotechnol Biochem. 2022 Aug 24;86(9):1255-1261. DOI:10.1093/bbb/zbac101

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