3-(METHYLTHIO)ANILINE Chemical Properties

Boiling point:

163-165 °C16 mm Hg(lit.)

Density 

1.13 g/mL at 25 °C(lit.)

vapor pressure 

1.66Pa at 25℃

refractive index 

n20/D 1.637(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

form 

clear liquid

pka

3.96±0.10(Predicted)

Specific Gravity

1/130

color 

Colorless to Light orange to Yellow

BRN 

2078599

LogP

1.68

CAS DataBase Reference

1783-81-9(CAS DataBase Reference)

NIST Chemistry Reference

3-CH3SC6H4NH2(1783-81-9)

EPA Substance Registry System

m-(Methylthio)aniline (1783-81-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

RIDADR 

UN 2810 6.1/PG 3

WGK Germany 

3

RTECS 

BY6301000

F 

2-8-13

Hazard Note 

Harmful

TSCA 

T

HazardClass 

IRRITANT, STENCH

HazardClass 

6.1

HS Code 

29309090

Toxicity

LD50 orl-qal: 750 mg/kg AECTCV 12,355,83

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-(METHYLTHIO)ANILINE Usage And Synthesis

Chemical Properties

clear dark brown liquid

Uses

Pharmaceutical intermediate.

Uses

3-(Methylthio)aniline was used in the synthesis of phenyl azobenzene sulfonamide derivatives.

Hazard

See aniline.

Safety Profile

Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors ofNO_x and SO_x.

Purification Methods

Purify the aniline by fractional distillation in an inert atmostphere. It has UV max at 226 and 300nm. [Bordwell & Cooper J Am Chem Soc 74 10581952.] The N-acetyl derivative has m 78-78.5o (from aqueous EtOH). The hydrochloride has m 260-261o (aqueous EtOH/HCl) or m 225-227o (EtOH/Et2O). [Beilstein 13 H 533, 13 III 1221, 13 IV 1289.]

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