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D-ERYTHRONOLACTONE

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D-ERYTHRONOLACTONE Basic information

Product Name:
D-ERYTHRONOLACTONE
Synonyms:
  • (2R,3R)-BUTANE-2,3,4-TRIOL-1,4 LACTONE
  • (3R)-CIS-4,5-DIHYDRO-3,4-DIHYDROXY-2(3H)-FURANONE
  • (3R-CIS) (-)-DIHYDRO-3,4-DIHYDROXY-2(3H)-FURANONE
  • (3R,4R)-(-)-D-ERYTHRONOLACTONE
  • (3R,4R)-DIHYDROXYDIHYDRO-2(3H)-FURANONE
  • (3R,4R)-(-)-D-ERYTHRONOLACTONE 99.5+%
  • d-erythronic acid γ-lactone
  • D-ERYTHRONIC ACID GAMMA-LACTONE
CAS:
15667-21-7
MF:
C4H6O4
MW:
118.09
Product Categories:
  • Chiral Reagents
  • chiral
  • Biochemistry
  • Chiral Building Blocks
  • Erythrose
  • Simple Alcohols (Chiral)
  • Sugar Acids
  • Sugars
  • Synthetic Organic Chemistry
Mol File:
15667-21-7.mol
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D-ERYTHRONOLACTONE Chemical Properties

Melting point:
100-102 °C(lit.)
Boiling point:
140.59°C (rough estimate)
Density 
1.0887 (rough estimate)
refractive index 
-71 ° (C=1, H2O)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
12.34±0.40(Predicted)
color 
White to Off-White
optical activity
[α]20/D 71°, c = 1 in H2O
BRN 
81073
CAS DataBase Reference
15667-21-7(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29322090

MSDS

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D-ERYTHRONOLACTONE Usage And Synthesis

Chemical Properties

D-ERYTHRONOLACTONE is white to light yellow crystal powde

Uses

D-ERYTHRONOLACTONE is a chiral synthon used for the synthesis of certain natural products such as the leukotrienes

Uses

D-erythrono-1,4-lactone is a potential substrates of dihydroxy acid dehydratase.

Uses

A chiral synthon used for the synthesis of certain natural products such as the leukotrienes.

Definition

ChEBI: Erythrono-1,4-lactone is a butan-4-olide that is dihydrofuran-2-one substituted at C-3 and C-4 by hydroxy groups (the 3R,4R-diastereomer). It is a butan-4-olide and a diol.

Purification Methods

Recrystallise it from EtOAc (20 parts) or isoPrOH (3 parts). [Baker & MacDonald J Am Chem Soc 82 230 1960, Glattfeld & Forbrich J Am Chem Soc 56 1209 1934, Weidenhagen & Wegner Chem Ber 72 2010 1939, Musich & Rapoport J Am Chem Soc 100 4865 1978, Beilstein 18/2 V 457.]

D-ERYTHRONOLACTONESupplier

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