2,3-O-Isopropylidene-D-ribonic gamma-lactone Chemical Properties

Melting point:

135-139 °C

alpha 

-68.5 º (c=2, Pyridine)

Boiling point:

243.17°C (rough estimate)

Density 

1.2069 (rough estimate)

refractive index 

1.4348 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in methanol at 50mg/ml, acetone, dichloromethane, ethyl Acetate.

form 

Powder

pka

13.68±0.10(Predicted)

color 

White to Off-white

optical activity

[α]20/D 69°, c = 2 in pyridine

Water Solubility 

soluble

BRN 

10090

CAS DataBase Reference

30725-00-9(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

29322090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2,3-O-Isopropylidene-D-ribonic gamma-lactone Usage And Synthesis

Description

2,3-Isopropylidene-D-ribonolactone is a building block. It has been used in the stereocontrolled synthesis of the carbohydrates 6-epi-trehazolin and 6-epi-trehalamine.

Chemical Properties

White Crystalline Solid

Uses

2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone is used for the synthesis of C-nucleosides, prostanoids and GABA analogs via homochiral 2-piperidones. It is the starting material for the preparation of biochemical compounds including C-nucleosides, such as neplanocin A, and GABA analogs, via homochiral 2-piperidones.

2,3-O-Isopropylidene-D-ribonic gamma-lactone(30725-00-9)Related Product Information

• N,N-Diisopropylethylamine
• N-Methyl-2-pyrrolidone
• TRIOXSALEN
• Diisopropylamine
• 2-Bromopropane
• Isoproterenol
• 3-Methyl-2-butanone
• Heptafluoroisopropyl iodide
• Cumene
• (R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXYLIC ACID METHYL ESTER
• (S)-3-Hydroxy-gamma-butyrolactone
• (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
• D-Ribose
• 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE
• D-ERYTHRONOLACTONE
• 5-Deoxy-D-ribose
• D(+)-Ribonic acid gamma-lactone
• 2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde