Methyl 4-amino-2-chlorobenzoate Chemical Properties

Melting point:

112-114°C

Boiling point:

334.2±22.0 °C(Predicted)

Density 

1.311±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

soluble in Chloroform

form 

powder to crystal

pka

1.41±0.10(Predicted)

color 

White to Almost white

InChI

InChI=1S/C8H8ClNO2/c1-12-8(11)6-3-2-5(10)4-7(6)9/h2-4H,10H2,1H3

InChIKey

DSHBGNPOIBSIOQ-UHFFFAOYSA-N

SMILES

C(OC)(=O)C1=CC=C(N)C=C1Cl

CAS DataBase Reference

46004-37-9(CAS DataBase Reference)

Safety Information

HS Code 

2916399090

Methyl 4-amino-2-chlorobenzoate Usage And Synthesis

Chemical Properties

off white powder

Uses

Methyl 4-Amino-2-chlorobenzoate is used as a reagent to synthesize selective LXR agonists that increase HDL levels and reverse cholesterol transport in mice.

References

[1] Patent: WO2010/65760, 2010, A1. Location in patent: Page/Page column 150
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 4, p. 1546 - 1562
[3] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 17, p. 4377 - 4381
[4] Acad. romine Stud. Cerc. Chim., 1956, vol. 4, p. 175,177
[5] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2991 - 3013

Methyl 4-amino-2-chlorobenzoate(46004-37-9)Related Product Information

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• Bensulfuron methyl
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• Methylparaben
• METHYL THIOPHENE-2-CARBOXYLATE
• Glycine
• Methyl anthranilate
• Methyl 4-aminobenzoate
• Methyl acetate
• Methyl formate
• Methyl benzoate
• Methyl 2-bromobenzoate
• Kresoxim-methyl
• METHYL 4-AMINO-3-CHLOROBENZOATE
• Thiophanate-methyl
• Methyl
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