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N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine

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N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine Basic information

Product Name:
N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine
Synonyms:
  • (S)-2-(((9H-fluoren-9-yl)methyl9H-fluoren-9-yl)methoxy)carbonylamino)-6-((4-methoxyphenyl)diphenylmethylamino)hexanoic acid
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-[(4-methoxyphenyl)diphenylmethyl]-L-lysine
  • N6-(4-Methoxytrityl)-L-lysine, N2-FMOC protected
  • N6-[Diphenyl(4-methoxyphenyl)methyl]-N2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-lysine, FMOC-L-LYS(MMT)-OH
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexanoic acid
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)hexan
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(((4-Methoxyphenyl)diphenylmethyl)amino)he
  • Nα-Fmoc-Nε-4-methoxyyltrityl-L-lysine≥ 99.8% (HPLC, Chiral purity)
CAS:
159857-60-0
MF:
C41H40N2O5
MW:
640.77
Product Categories:
  • amino acids
Mol File:
159857-60-0.mol
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N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine Chemical Properties

Boiling point:
814.1±65.0 °C(Predicted)
Density 
1.210
storage temp. 
Store at +2°C to +8°C.
pka
3.83±0.21(Predicted)
form 
solid
color 
off-white
Major Application
peptide synthesis
InChIKey
CTYHQVFFQRDJSN-LHEWISCISA-N
SMILES
C(O)(=O)[C@H](CCCCNC(C1=CC=C(OC)C=C1)(C1=CC=CC=C1)C1=CC=CC=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
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Safety Information

WGK Germany 
WGK 3
HS Code 
2924297099
Storage Class
11 - Combustible Solids
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N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine Usage And Synthesis

Chemical Properties

White to pale brown solid

Uses

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysine is used in peptide synthesis.

General Description

An excellent derivative for the synthesis of branched peptides and peptides modified at the lysine side-chain [1], and for the construction of templates and multifunctionalized resins for combinatorial synthesis.

The side-chain Mmt group can be selectively removed in the same manner as Mtt with 1% TFA in DCM [2, 3, 4] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [5]. Alternatively, it can be removed under milder conditions with AcOH/TFE/DCM (1:2:7) [1], leaving Mtt intact.

The product number for this product was previously 04-12-1232.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

N-alpha-Fmoc-N-epsilon-4-methoxytrityl-L-lysineSupplier

SANBEM Biotech (Suzhou) Co., Ltd. Gold
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Chengdu Yontinotech Co.,Ltd Gold
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028-86293627 15228898511
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Shandong Zhengtuo Pharmaceutical Technology Co., Ltd. Gold
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15666908650
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Sichuan Tongsheng Amino acids Co.,Ltd.
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0838-2274206 13908101207
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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