ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Serine derivatives > FMOC-O-tert-Butyl-L-serine
FMOC-O-tert-Butyl-L-serine
FMOC-O-tert-Butyl-L-serine Basic information
- Product Name:
- FMOC-O-tert-Butyl-L-serine
- Synonyms:
-
- FMOC-L-Ser(tBu)-OH 98%
- O-tert-Butyl-N-Fmoc-L-serine
- 9-fluorenylmethoxycarbonyl-O-tert-butyl-L-serine
- N-Fmoc-O-tert-Butyl-L-serine, Fmoc-O-tert-butyl-L-serine
- N-FMOC-L-Ser (O-tert-Bu) OH
- 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]propanoic acid
- N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butyl-L-serine
- N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-tert-butylserine
- CAS:
- 71989-33-8
- MF:
- C22H25NO5
- MW:
- 383.44
- EINECS:
- 276-260-6
- Product Categories:
-
- Amino Acids (N-Protected)
- Biochemistry
- Serine [Ser, S]
- Fmoc-Amino Acids and Derivatives
- Fmoc-Amino Acids
- Fmoc-Amino acid series
- Fluorenes, Flurenones
- Amino Acids
- Mol File:
- 71989-33-8.mol
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FMOC-O-tert-Butyl-L-serine Chemical Properties
- Melting point:
- 130.5-135.5 °C(lit.)
- alpha
- 25 º (c=1,EtOAc 24 ºC)
- Boiling point:
- 510.36°C (rough estimate)
- Density
- 1.2369 (rough estimate)
- refractive index
- 24 ° (C=1, AcOEt)
- storage temp.
- 2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 3.44±0.10(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- optical activity
- [α]20/D +25.5±1°, c = 1% in ethyl acetate
- BRN
- 3632013
- InChI
- InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
- InChIKey
- REITVGIIZHFVGU-IBGZPJMESA-N
- SMILES
- C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
- CAS DataBase Reference
- 71989-33-8(CAS DataBase Reference)
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36/37/39-27-26
- WGK Germany
- 3
- HS Code
- 29242990
MSDS
- Language:English Provider:FMOC-O-tert-Butyl-L-serine
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
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FMOC-O-tert-Butyl-L-serine Usage And Synthesis
Chemical Properties
white to light yellow crystal powde
Uses
Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:
- Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
- Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
- Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.
General Description
The product number for this product was previously 04-12-1033.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
FMOC-O-tert-Butyl-L-serine Preparation Products And Raw materials
Raw materials
FMOC-O-tert-Butyl-L-serineSupplier
Lanxi Xingnuo Import and Export Trading Co., Ltd Gold
- Tel
- 15888978871 15888978871
- 994350525@qq.com
Nanjing Peptide Biotech Ltd. Gold
- Tel
- 025-58361106-805 13082558573
- liugang@njpeptide.com
Chengdu Aminotp Pharmaceutical Technology Co.,Ltd. Gold
- Tel
- 028-85755578 18140172005
- sales@aminotp.com
Chengdu Tachem Co., Ltd Gold
- Tel
- 028-61682518; 19983060238
- sales@tachem.cn
shanghai Yanfeng biochemical technology Co.,LTD Gold
- Tel
- 021-13611955358 13611955358
- yanfen2023@126.com
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FMOC-O-tert-Butyl-L-serine(71989-33-8)Related Product Information
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