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N-(9-Fluorenylmethoxycarbonyloxy)succinimide

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N-(9-Fluorenylmethoxycarbonyloxy)succinimide Basic information

Product Name:
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Synonyms:
  • 1-[[(9h-fluoren-9-ylmethoxy)carbonyl]oxy]-5-pyrrolidinedione
  • 9-fluorenylmethoxycarbonyloxysuccinimide
  • 9-fluorenylmethyl-n-succinimide carbonate
  • N-(9-FluorenylmethoxyCarbonyloxy)Succinimide9-Fluorenylmethylsuccinimidylcarbonate
  • CARBONIC ACID 2,5-DIOXO-PYRROLIDIN-1-YL ESTER 9H-FLUOREN-9-YLMETHYL ESTER
  • CARBONIC ACID FLUORENYLMETHYL SUCCIN-N-YL-ESTER
  • FMOC-OSU
  • FMOC-ONSU
CAS:
82911-69-1
MF:
C19H15NO5
MW:
337.33
EINECS:
433-520-5
Product Categories:
  • Fmoc-OSU
  • peptides
  • Medical Intermediates
  • Benzocycles
  • Fluorenes, Flurenones
  • Pyrrolidines
  • Amino Acid Derivatives
  • N-Protecting Reagents
  • Biochemistry
  • Condensation & Active Esterification
  • Fluorenes
  • Fluorenes & Fluorenones
  • Heterocycles
  • Miscellaneous Reagents
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Succinimides
  • Peptide Synthesis
  • Protective Reagents (Peptide Synthesis)
  • Synthetic Organic Chemistry
  • Fmoc-Amino acid series
  • bc0001
Mol File:
82911-69-1.mol
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N-(9-Fluorenylmethoxycarbonyloxy)succinimide Chemical Properties

Melting point:
150-153 °C(lit.)
Boiling point:
150-153°C
Density 
1.3460 (rough estimate)
refractive index 
1.5000 (estimate)
storage temp. 
2-8°C
solubility 
Soluble in dimethyl sulfoxide and dimethyl formamide.
form 
Microfine Powder
color 
White or almost white
Sensitive 
Moisture Sensitive
BRN 
3569540
Stability:
Moisture Sensitive
CAS DataBase Reference
82911-69-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,N,Xn
Risk Statements 
36/37/38-51/53-43-22
Safety Statements 
22-24/25-26/37/39-26-61-37-24
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
10-21
Hazard Note 
Moisture Sensitive
HazardClass 
9
HS Code 
29251995

MSDS

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N-(9-Fluorenylmethoxycarbonyloxy)succinimide Usage And Synthesis

Chemical Properties

White powder

Uses

N-protecting reagent for oligonucleotide and peptide syntheses

Uses

Reagent for the preparation of pure Fmoc amino acids free from contamination by Fmoc-dipeptides.

Uses

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.

Purification Methods

Recrystallise the carbonate from CHCl3/Et2O, or from pet ether (b 40-60o). [Pauet Can J Chem 60 976 1982, Lapatsaris et al. Synthesis 671 1983.]

N-(9-Fluorenylmethoxycarbonyloxy)succinimide Preparation Products And Raw materials

Preparation Products

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