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TBTA

Basic information Safety Supplier Related

TBTA Basic information

Product Name:
TBTA
Synonyms:
  • Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)Methyl]aMine 97%
  • 1-(1-Benzyltriazol-4-yl)-N,N-bis[(1-benzyltriazol-4-yl)methyl]methanamine
  • N,N,N-Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine
  • Tris-(benzyltriazolylmethyl)amine
  • Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine
  • Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine, 97% TBTA
  • 1H-1,2,3-Triazole-4-methanamine, 1-(phenylmethyl)-N,N-bis[[1-(phenylmethyl)-1H-1,2,3-triazol-4-yl]methyl]-
  • TBTA ISO 9001:2015 REACH
CAS:
510758-28-8
MF:
C30H30N10
MW:
530.63
EINECS:
693-028-3
Mol File:
510758-28-8.mol
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TBTA Chemical Properties

Melting point:
132-143℃
Boiling point:
762.4±70.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO, DMF.
pka
2.44±0.50(Predicted)
form 
Solid
color 
White
Stability:
store cold
InChI
InChI=1S/C30H30N10/c1-4-10-25(11-5-1)16-38-22-28(31-34-38)19-37(20-29-23-39(35-32-29)17-26-12-6-2-7-13-26)21-30-24-40(36-33-30)18-27-14-8-3-9-15-27/h1-15,22-24H,16-21H2
InChIKey
WKGZJBVXZWCZQC-UHFFFAOYSA-N
SMILES
N1(CC2=CC=CC=C2)C=C(CN(CC2=CN(CC3=CC=CC=C3)N=N2)CC2=CN(CC3=CC=CC=C3)N=N2)N=N1
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Safety Information

WGK Germany 
3
HS Code 
2933998090
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TBTA Usage And Synthesis

Description

TBTA was introduced shortly after the copper-catalyzed azide-alkyne cycloaddition reaction was discovered to mitigate thermodynamic instability of Cu(I) in aerobic media. TBTA is a water-insoluble ligand and must be first dissolved in DMSO or DMF. J Am Chem Soc., 143 (18), 6787-6791. T. R. Chan, R. Hilgraf, K. B. Sharpless, V. V. Fokin, Org. Lett. 2004, 6, 2853.

Uses

Tris-(benzyltriazolylmethyl)amine is a useful reagent for copper (I) catalyzed azide-alkyne cycloadditions.?It can also be used for postsynthetic labelling of alkyne-modified DNA.

storage

Store at -20°C

TBTASupplier

Xianning Shen Lan Biomedical Research and Development Co., Ltd. Gold
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