- Product Name:
- Benzyl bromide
- ??benzyl bromide? (100-39-0?)??
- Product Categories:
- Reagents for Oligosaccharide Synthesis
- Building Blocks
- Chemical Synthesis
- Halogenated Hydrocarbons
- Pharmaceutical Intermediates
- Aromatic Halides (substituted)
- Organic Building Blocks
- Mol File:
Benzyl bromide Chemical Properties
- Melting point:
- -3 °C
- Boiling point:
- 198-199 °C(lit.)
- 1.44 g/mL at 20 °C
- vapor density
- 5.8 (vs air)
- vapor pressure
- 0.5 hPa (20 °C)
- refractive index
- n20/D 1.575(lit.)
- Flash point:
- 188 °F
- storage temp.
- Store below +30°C.
- Miscible with benzene, carbon tetrachloride, ethanol and ether.
- Clear colorless to yellow
- Very sharp, pungent, like tear gas.
- Moisture Sensitive/Light Sensitive
- Stable. Combustible. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 100-39-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, (bromomethyl)-(100-39-0)
- EPA Substance Registry System
- Benzyl bromide (100-39-0)
Benzyl bromide Usage And Synthesis
Clear light amber liquid
Benzylbromide is a combustible, colorless to yellow liquid with a pleasant odor. Molecular
Making foaming and frothing agents, organic synthesis.
ChEBI: A member of the class of benzyl bromides that is toluene substituted on the alpha-carbon with bromine.
Journal of the American Chemical Society, 95, p. 3412, 1973 DOI: 10.1021/ja00791a072
Tetrahedron Letters, 29, p. 707, 1988 DOI: 10.1016/S0040-4039(00)80190-2
The Journal of Organic Chemistry, 51, p. 929, 1986 DOI: 10.1021/jo00356a032
A colorless liquid with an agreeable odor. Toxic by inhalation and by skin absorption. Benzyl bromide is slightly soluble in water and denser than water (density 1.44 g / cm3 (Aldrich)). A lachrymator. Corrosive to metals and tissue.
Air & Water Reactions
Sensitive to exposure to light and moisture. Slightly soluble in water.
Benzyl bromide reacts with water, alcohols, common metals (except nickel and lead), bases, amines and oxidizing agents. . Benzyl bromide stored over activated 4A molecular sieve burst a bottle due to condensation-polymerization reaction with generation of HBr gas, [Chem. Eng. News, 1979, 57(12), 74].
Highly toxic. Corrosive to skin and tissue. A lachrymator.
Inhalation causes irritation of nose and throat; severe exposure may cause pulmonary edema. Vapors cause severe eye irritation; liquid can burn eyes. Skin contact causes irritation. Ingestion causes irritation of mouth and stomach.
Reactivity with Water Reacts slowly generating hydrogen bromide (hydrobromic acid); Reactivity with Common Materials: Decomposes rapidly in the presence of all common metals except nickel and lead, liberating heat and hydrogen bromide; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Rinse with sodium bicarbonate or lime solution; Polymerization: Polymerizes with evolution of heat and hydrogen bromide when in presence with all common metals except nickel and lead; Inhibitor of Polymerization: None.
Intensely irritating and corrosiveto skin, eyes, and mucous membranes. Large doses causecentral nervous system depression. Mutation datareported. Reaction with molecular sieve produces toxichydrogen bromide gas.
It is used as a chemical intermediate; in organic syntheses; as a foaming and frothing agent.
UN1737 Benzyl Bromide, Hazard class: 6.1; Labels: 6.1—Poisonous materials, 8—Corrosive material.
Wash benzyl chloride with conc H2SO4 (CARE), water, 10% Na2CO3 or NaHCO3 solution, and again with water. Dry it with CaCl2, Na2CO3 or MgSO4 and fractionally distil it in the dark, under reduced pressure. It has also been thoroughly degassed at 10-6 mm and redistilled in the dark. This gives material with max (MeCN): 226nm ( 8200) [Mohammed & Kosower J Am Chem Soc 93 2709 1971]. [Beilstein 5 IV 829.] Handle in a fume cupboard, extremely LACHRYMATORY.
May form explosive mixture with air. Contact with water forms hydrogen bromide and benzyl alcohol. Incompatible with strong oxidizers, bases, magnesium. Attacks metals, except nickel and lead, in the presence of moisture.
Pour into vermiculite, sodium bicarbonate, or a sand-soda ash mixture and transfer to paper boxes, then to an open incinerator. Alternatively, mix Benzyl Bromide 417 with flammable solvent and spray into incinerator equipped with after burner and alkali scrubber.
Benzyl bromide Preparation Products And Raw materials
- Sodium bromide
- 2-Ethylhexyl bromide
- Calcium bromide
- Bromoacetyl bromide
- Ammonium bromide
- NICKEL BROMATE
- Potassium bromide
- Cupric bromide
- Zinc bromide
- BENZYL GLYCIDYL ETHER
- Benzyltrimethylammonium chloride