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D-(+)-MELEZITOSE

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D-(+)-MELEZITOSE Basic information

Product Name:
D-(+)-MELEZITOSE
Synonyms:
  • D-(+)-MELEZITOSE
  • D-MELEZITOSE
  • alpha-d-glucopyranoside,o-alpha-d-glucopyranosyl-(1.fwdarw.3)-beta-d-fructo
  • furanosyl
  • O-ALPHA-D-GLUCOPYRANOSYL-(1-3)-BETA-D-FRUCTOFURANOSYL-ALPHA-D-GLUCOPYRANOSIDE
  • MELEZITOSE
  • melizitose
  • D-MELEZITOSE MONOHYDRATE, FOR BACTERIOLOGY
CAS:
597-12-6
MF:
C18H32O16
MW:
504.44
EINECS:
209-894-9
Product Categories:
  • Basic Sugars (Mono & Oligosaccharides)
  • Biochemistry
  • Sugars
  • Trisaccharides
Mol File:
597-12-6.mol
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D-(+)-MELEZITOSE Chemical Properties

Melting point:
153°C
Boiling point:
513.84°C (rough estimate)
Density 
1.5565
refractive index 
88.5 ° (C=4, H2O)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Soluble (water), slightly soluble (ethanol)
form 
Solid
pka
12.83±0.70(Predicted)
color 
White to off-white
optical activity
+88.8
Water Solubility 
Water : ≥ 31 mg/mL (61.45 mM)
Merck 
5819
LogP
-5.790 (est)
CAS DataBase Reference
597-12-6(CAS DataBase Reference)
EPA Substance Registry System
Melezitose (597-12-6)
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Safety Information

HS Code 
29400090
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D-(+)-MELEZITOSE Usage And Synthesis

Uses

d-(+)-Melezitose can be used to treat cancer, autoimmune diseases and infectious diseases.

Definition

ChEBI: A trisaccharide produced by insects such as aphids.

Purification Methods

D(+)-Melezitose crystallises from aqueous EtOH as the monohydrate and water as the dihydrate, and is then dried at 110o (anhydrous). It is also purified by dissolving in an equal volume of H2O, filtering into a crystallising dish and allowing to stand (loosely covered) for several weeks undisturbed at 20o. The crystals of clear prisms are wiped carefully and dried in air. They effloresce at once losing 3.35% of their weight, and after 3days in air the loss is for 1H2O from the dihydrate. Drying at 110o for 6hours in vacuo yields the anhydrous form which after 2days in air it absorbs H2O to give the monohydrate. The monohydrate is also obtained by dissolving it in an equal weight of H2O at 60o and adding 4 volumes of 95% EtOH and drying in air overnight. [Richtmeyer & Hudson J Org Chem 11 610 1946, Beilstein 17 III/IV 3815, 17/8 V 414.]

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