2,2-Diethoxypropane Chemical Properties

Boiling point:

116-117 °C (lit.)

Density 

0.82 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.389(lit.)

Flash point:

46 °F

storage temp. 

2-8°C

form 

clear liquid

color 

Colorless to Almost colorless

CAS DataBase Reference

126-84-1(CAS DataBase Reference)

NIST Chemistry Reference

Propane, 2,2-diethoxy-(126-84-1)

EPA Substance Registry System

Propane, 2,2-diethoxy- (126-84-1)

Safety Information

Hazard Codes 

F

Risk Statements 

11

Safety Statements 

16-29-33

RIDADR 

UN 3271 3/PG 2

WGK Germany 

3

RTECS 

AL4900000

TSCA 

Yes

HazardClass 

3.1

PackingGroup 

II

HS Code 

29110000

Toxicity

LD50 ipr-mus: 125 mg/kg NTIS** AD277-689

MSDS

• Language:English Provider:Acetone diethyl acetal
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,2-Diethoxypropane Usage And Synthesis

Uses

Ethereal-camphorlike odor. Probably not used in flavors.Occasionally used in perfumes to introduce diffusive topnotes in herbaceous-camphoraceous blends (Lavandin-Rosemary, etc.).

Production Methods

2,2-Diethoxypropane can be produced by synthesis via orthoformic ester, or via vinyl ether, or via formiminoethylether hydrochloride.

Preparation

To a flask equipped as in Preparation 2-11 and containing 1725 gm (37.5 moles) of ethanol, 18.4 gm (0.058 mole) of mercuric acetate, and 28 ml of 26% boron fluoride etherate (26%) at 30°C is added dropwise over a 15 min period at 45-50°C, 1250 gm (12.5 moles) of isopropenyl acetate. After the reaction 2200 gm of 25% sodium hydroxide is added, the organic layer separated, washed first with 400 ml of 0.01 Ν sodium hydroxide, dried, and distilled to afford 1140 gm (69%), b.p. 110-113 C (760 mm Hg).

Safety Profile

Poison by intraperitoneal route.When heated to decomposition it emits acrid smoke.

Solubility in organics

Soluble in alcohol, miscible with CSS.oils and perfume chemicals.

2,2-Diethoxypropane (126-84-1)Related Product Information

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• 4-Ethoxyphenol
• DIETHOXYMETHANE
• Ethoxyquin
• Ethylene glycol diethyl ether
• Acetal
• Diethylene Glycol Monoethyl Ether
• 2,2-Dimethoxypropane
• Diethyl oxalate
• acetic acid, triethoxy-, ethyl ester
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• Celiprolol
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• HECOGENIN ACETATE
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