NITROCYCLOPENTANE Chemical Properties

Melting point:

143-144 °C

Boiling point:

180 °C (lit.)

Density 

1.086 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.454(lit.)

Flash point:

153 °F

pka

8.46±0.20(Predicted)

BRN 

907079

CAS DataBase Reference

2562-38-1

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

RIDADR 

2810

WGK Germany 

3

RTECS 

GY4657500

HazardClass 

6.1

PackingGroup 

III

HS Code 

29042000

MSDS

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NITROCYCLOPENTANE Usage And Synthesis

Chemical Properties

Clear pale yellow liquid

Preparation

Bromocyclopentane (22.0 g, 0.15 mol) was added to a soln of NaNO2 (18 g, 0.26 mol) in dry DMSO (100 mL) at 15 ℃ and the mixture was stirred at this temperature for 3 h. The mixture was poured into ice water (250 mL) and extracted with petroleum ether (bp 35-37 ℃; 4 × 50 mL). The combined organic extracts were washed with H2O (4× 50 mL), dried (MgSO4), and concentrated under reduced pressure. The residue was distilled to give Nitrocyclopentane; yield: 9.9 g (58%); bp 62 ℃/8 Torr; nD/20 1.4538.

Synthesis of Nitrocyclopentane

Synthesis Reference(s)

Tetrahedron Letters, 21, p. 1117, 1980 DOI: 10.1016/S0040-4039(01)83928-9

General Description

Nitrocyclopentane, a secondary nitroalkane, was examined for its ability to induce DNA repair in rat hepatocytes. The nitronate of nitrocyclopentane was mutagenic in Salmonella strains TA100 and TA102.

NITROCYCLOPENTANE(2562-38-1)Related Product Information

• (NITROMETHYL)BENZENE
• Amylamine
• N-Isopropylhydroxylamine
• Allylamine hydrochloride
• 2-Nitropropane
• 1-Nitropropane
• 3-Aminopentane
• Nitromethane
• HYDROXYLAMINE
• 1-NITROBUTANE
• Cyclopentane
• Ammonium hydroxide
• sec-Butylamine
• 2-Nitrobutane
• Propylamine
• 2-AMINOPENTANE
• Nitroethane
• (R)-(-)-2-Aminobutane